Does CBD induce apoptosis in diffuse large B cell lymphoma?

This study assessed the ability of cannabidiol (CBD), a compound derived from cannabis, to induce apoptosis in diffuse large B-cell lymphoma (DLBCL). This experiment consisted of cell viability assays and apoptosis assays, both of which measure important qualities needed in cancer treatment. CBD dem...

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Bibliographic Details
Main Author: Xu, S.
Format: Article
Language:English
Published: Royal St. George's College 2018-08-01
Series:The Young Researcher
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Online Access:http://www.theyoungresearcher.com/papers/xu.pdf
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Summary:This study assessed the ability of cannabidiol (CBD), a compound derived from cannabis, to induce apoptosis in diffuse large B-cell lymphoma (DLBCL). This experiment consisted of cell viability assays and apoptosis assays, both of which measure important qualities needed in cancer treatment. CBD demonstrated a strong capability in inhibiting cell viability, at concentrations near 50-100 uM, thereby emphasizing its potential in minimizing relapse. CBD actively induced apoptosis at concentrations above 25 uM, with apoptosis frequencies reaching nearly 100%. These results reinforce the idea that CBD induces apoptosis throughout many different types of cancers, including DLBCL. Thus, this study demonstrates that CBD has a great potential in cancer treatment by eradicating cancer cells in DLBCL.
ISSN:2560-9823
2560-9823