The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucoma

Vitamin E, encompassing tocopherols and tocotrienols is celebrated for its powerful antioxidant properties, which help neutralize free radicals and protect cells from oxidative damage. Over the years, research has shown that both tocopherols and tocotrienols offer significant benefits, including pro...

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Main Authors: Fazira Latib, Muhamad Arif Irfan Zafendi, Mohd Aizuddin Mohd Lazaldin
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Food Chemistry: Molecular Sciences
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666566224000315
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author Fazira Latib
Muhamad Arif Irfan Zafendi
Mohd Aizuddin Mohd Lazaldin
author_facet Fazira Latib
Muhamad Arif Irfan Zafendi
Mohd Aizuddin Mohd Lazaldin
author_sort Fazira Latib
collection DOAJ
description Vitamin E, encompassing tocopherols and tocotrienols is celebrated for its powerful antioxidant properties, which help neutralize free radicals and protect cells from oxidative damage. Over the years, research has shown that both tocopherols and tocotrienols offer significant benefits, including protection against radiation damage, cholesterol regulation, cardiovascular health, and neurological disorders. This wide range of benefits highlights the need for further exploration of vitamin E’s role in managing various diseases. One particularly promising area is its potential application in treating ocular diseases like glaucoma. Despite advances in treatment, current options have limitations, making the investigation of alternative approaches crucial. Omics technologies, which allow for a detailed examination of biological systems, could provide valuable insights into how tocopherols and tocotrienols work at a molecular level. Their neuroprotective and antioxidative properties make them promising candidates for glaucoma management. Additionally, the sustainability of vitamin E is noteworthy, as by-products from its production can be repurposed into valuable resources for nutraceuticals and pharmaceuticals. As research continues, integrating omics technologies with the study of vitamin E derivatives could unveil new therapeutic possibilities, further enhancing our understanding of its diverse health benefits and its potential role in preventing and managing diseases.
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spelling doaj-art-362fa3a1d5d84eef8773587c6e8d922d2025-08-20T02:50:16ZengElsevierFood Chemistry: Molecular Sciences2666-56622024-12-01910022410.1016/j.fochms.2024.100224The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucomaFazira Latib0Muhamad Arif Irfan Zafendi1Mohd Aizuddin Mohd Lazaldin2Department of Biosciences, Faculty of Science, Universiti Teknologi Malaysia, Johor Bahru, MalaysiaDepartment of Biosciences, Faculty of Science, Universiti Teknologi Malaysia, Johor Bahru, MalaysiaCorresponding author.; Department of Biosciences, Faculty of Science, Universiti Teknologi Malaysia, Johor Bahru, MalaysiaVitamin E, encompassing tocopherols and tocotrienols is celebrated for its powerful antioxidant properties, which help neutralize free radicals and protect cells from oxidative damage. Over the years, research has shown that both tocopherols and tocotrienols offer significant benefits, including protection against radiation damage, cholesterol regulation, cardiovascular health, and neurological disorders. This wide range of benefits highlights the need for further exploration of vitamin E’s role in managing various diseases. One particularly promising area is its potential application in treating ocular diseases like glaucoma. Despite advances in treatment, current options have limitations, making the investigation of alternative approaches crucial. Omics technologies, which allow for a detailed examination of biological systems, could provide valuable insights into how tocopherols and tocotrienols work at a molecular level. Their neuroprotective and antioxidative properties make them promising candidates for glaucoma management. Additionally, the sustainability of vitamin E is noteworthy, as by-products from its production can be repurposed into valuable resources for nutraceuticals and pharmaceuticals. As research continues, integrating omics technologies with the study of vitamin E derivatives could unveil new therapeutic possibilities, further enhancing our understanding of its diverse health benefits and its potential role in preventing and managing diseases.http://www.sciencedirect.com/science/article/pii/S2666566224000315Vitamin ETocopherolTocotrienolGlaucomaIntraocular pressurePhytochemistry
spellingShingle Fazira Latib
Muhamad Arif Irfan Zafendi
Mohd Aizuddin Mohd Lazaldin
The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucoma
Food Chemistry: Molecular Sciences
Vitamin E
Tocopherol
Tocotrienol
Glaucoma
Intraocular pressure
Phytochemistry
title The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucoma
title_full The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucoma
title_fullStr The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucoma
title_full_unstemmed The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucoma
title_short The use of vitamin E in ocular health: Bridging omics approaches with Tocopherol and Tocotrienol in the management of glaucoma
title_sort use of vitamin e in ocular health bridging omics approaches with tocopherol and tocotrienol in the management of glaucoma
topic Vitamin E
Tocopherol
Tocotrienol
Glaucoma
Intraocular pressure
Phytochemistry
url http://www.sciencedirect.com/science/article/pii/S2666566224000315
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