Abnormal response to chronic social defeat stress and fear extinction in a mouse model of Lynx2-based cholinergic dysregulation

Abnormal response to chronic social defeat stress and fear extinction in a mouse model of Lynx2-based cholinergic dysregulation

Nicotinic receptor signaling is influential in modulating appropriate responses to salient stimuli within a complex environment. The cholinergic neurotransmitter system drives attention to salient stimuli such as stressors, and aids in orchestrating the proper neural and behavioral responses. Dysreg...

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Bibliographic Details
Main Authors: Kristin R. Anderson, Peter J. Rogu, Talulla B. Palumbo, Julie M. Miwa
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Neuroscience
Subjects:
nAChR
Lynx2
LYPD1
social interaction
anxiety behavior
nicotinic acetylcholine receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1466166/full
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