Quantitative 177Lu-DOTATATE SPECT/CT is predictive of 6-month PRRT morphological response in midgut neuroendocrine tumors: a pilot study

Quantitative 177Lu-DOTATATE SPECT/CT is predictive of 6-month PRRT morphological response in midgut neuroendocrine tumors: a pilot study

Abstract Background peptide receptor radionuclide therapy with 177Lu-DOTATATE has become an established second-line treatment for patients with advanced small intestine neuroendocrine tumors (siNET). Treatment efficacy is assessed several months after the end of treatment and is based on RECIST crit...

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Bibliographic Details
Main Authors: Iness Megherbi, Christopher Hoog, Marine Perrier, Hedia Brixi, Guillaume Cadiot, Christine Hoeffel-Fornes, David Morland
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:EJNMMI Research
Subjects:
Neuroendocrine tumors
Lutetium Lu 177 dotatate
Single photon emission computerized tomography
Online Access:https://doi.org/10.1186/s13550-025-01250-6
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