Effect of advanced glycation end products formed methylglyoxal, a food-borne dicarbonyl precursor, on the exacerbation of diabetic kidney disease by NOX4/Nrf2/NLRP3 inflammasome signaling pathway in db/db mice
Abstract Western-style diets, which are abundant in advanced glycation end products (AGEs), particularly methylglyoxal-derived AGE4, have been identified as contributing factors to the progression of diabetic kidney disease. The objective of this study was to elucidate the pathogenic mechanisms of A...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2025-07-01
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| Series: | Applied Biological Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13765-025-01011-y |
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