Decitabine combined with reduced-intensity conditioning for older patients with acute myeloid leukemia in composite complete remission undergoing allogeneic hematopoietic stem cell transplantation: a multicenter, single-arm, phase 2 trialResearch in context

Decitabine combined with reduced-intensity conditioning for older patients with acute myeloid leukemia in composite complete remission undergoing allogeneic hematopoietic stem cell transplantation: a multicenter, single-arm, phase 2 trialResearch in context

Summary: Background: Outcomes of older patients with acute myeloid leukemia (AML) undergoing allogeneic hematopoietic stem-cell transplantation (allo-HSCT) remain unsatisfactory. The primary objective of this trial was to establish whether decitabine combined with reduced-intensity conditioning (RI...

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Bibliographic Details
Main Authors: Qifa Liu, Zhongli Hu, Na Xu, Yirong Jiang, Zhiping Fan, Fen Huang, Ren Lin, Hua Jin, Yunxin Zeng, Hai He, Ping Zhu, Guopan Yu, Pengcheng Shi, Ruijuan Sun, Xiaojun Xu, Zhangkun Li, Yu Zhang, Jing Sun, Yu Wang, Li Xuan
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:The Lancet Regional Health. Western Pacific
Subjects:
Decitabine
Reduced-intensity conditioning
Older
Acute myeloid leukemia
Allogeneic hematopoietic stem cell transplantation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666606525002032
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