Phenotypic stasis with genetic divergence
Whether or not genetic divergence in the short-term of tens to hundreds of generations is compatible with phenotypic stasis remains a relatively unexplored problem. We evolved predominantly outcrossing, genetically diverse populations of the nematode Caenorhabditis elegans under a constant and homog...
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2023-12-01
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| Series: | Peer Community Journal |
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| Online Access: | https://peercommunityjournal.org/articles/10.24072/pcjournal.349/ |
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| author | Mallard, François Noble, Luke Guzella, Thiago Afonso, Bruno Baer, Charles F. Teotónio, Henrique |
| author_facet | Mallard, François Noble, Luke Guzella, Thiago Afonso, Bruno Baer, Charles F. Teotónio, Henrique |
| author_sort | Mallard, François |
| collection | DOAJ |
| description | Whether or not genetic divergence in the short-term of tens to hundreds of generations is compatible with phenotypic stasis remains a relatively unexplored problem. We evolved predominantly outcrossing, genetically diverse populations of the nematode Caenorhabditis elegans under a constant and homogeneous environment for 240 generations and followed individual locomotion behavior. Although founders of lab populations show highly diverse locomotion behavior, during lab evolution, the component traits of locomotion behavior – defined as the transition rates in activity and direction – did not show divergence from the ancestral population. In contrast, transition rates’ genetic (co)variance structure showed a marked divergence from the ancestral state and differentiation among replicate populations during the final 100 generations and after most adaptation had been achieved. We observe that genetic differentiation is a transient pattern during the loss of genetic variance along phenotypic dimensions under drift during the last 100 generations of lab evolution. These results suggest that short-term stasis of locomotion behavior is maintained because of stabilizing selection, while the genetic structuring of component traits is contingent upon drift history.
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| format | Article |
| id | doaj-art-360de8cea71a4fe590c325e16aedf19f |
| institution | Kabale University |
| issn | 2804-3871 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Peer Community In |
| record_format | Article |
| series | Peer Community Journal |
| spelling | doaj-art-360de8cea71a4fe590c325e16aedf19f2025-02-07T10:16:48ZengPeer Community InPeer Community Journal2804-38712023-12-01310.24072/pcjournal.34910.24072/pcjournal.349Phenotypic stasis with genetic divergence Mallard, François0https://orcid.org/0000-0003-2087-1914Noble, Luke1https://orcid.org/0000-0002-5161-4059Guzella, Thiago2Afonso, Bruno3Baer, Charles F.4https://orcid.org/0000-0002-0140-5814Teotónio, Henrique5https://orcid.org/0000-0003-1057-6882Institut de Biologie de l’École Normale Supérieure, CNRS UMR 8197, Inserm U1024, PSL Research University, F-75005 Paris, FranceInstitut de Biologie de l’École Normale Supérieure, CNRS UMR 8197, Inserm U1024, PSL Research University, F-75005 Paris, FranceInstitut de Biologie de l’École Normale Supérieure, CNRS UMR 8197, Inserm U1024, PSL Research University, F-75005 Paris, FranceInstitut de Biologie de l’École Normale Supérieure, CNRS UMR 8197, Inserm U1024, PSL Research University, F-75005 Paris, FranceDepartment of Biology, University of Florida Genetics Institute, University of Florida, Gainsville, Florida 32611, U.S.A.Institut de Biologie de l’École Normale Supérieure, CNRS UMR 8197, Inserm U1024, PSL Research University, F-75005 Paris, FranceWhether or not genetic divergence in the short-term of tens to hundreds of generations is compatible with phenotypic stasis remains a relatively unexplored problem. We evolved predominantly outcrossing, genetically diverse populations of the nematode Caenorhabditis elegans under a constant and homogeneous environment for 240 generations and followed individual locomotion behavior. Although founders of lab populations show highly diverse locomotion behavior, during lab evolution, the component traits of locomotion behavior – defined as the transition rates in activity and direction – did not show divergence from the ancestral population. In contrast, transition rates’ genetic (co)variance structure showed a marked divergence from the ancestral state and differentiation among replicate populations during the final 100 generations and after most adaptation had been achieved. We observe that genetic differentiation is a transient pattern during the loss of genetic variance along phenotypic dimensions under drift during the last 100 generations of lab evolution. These results suggest that short-term stasis of locomotion behavior is maintained because of stabilizing selection, while the genetic structuring of component traits is contingent upon drift history. https://peercommunityjournal.org/articles/10.24072/pcjournal.349/phenotypic stasisG-matrixselection surfacegenetic driftlocomotion behaviortransition ratesCaenorhabditis elegansexperimental evolutionphenotypic stasisG-matrixselection surfacegenetic driftlocomotion behaviortransition ratesCaenorhabditis elegansexperimental evolutionphenotypic stasisG-matrixselection surfacegenetic driftlocomotion behaviortransition ratesCaenorhabditis elegansexperimental evolution |
| spellingShingle | Mallard, François Noble, Luke Guzella, Thiago Afonso, Bruno Baer, Charles F. Teotónio, Henrique Phenotypic stasis with genetic divergence Peer Community Journal phenotypic stasis G-matrix selection surface genetic drift locomotion behavior transition rates Caenorhabditis elegans experimental evolution phenotypic stasis G-matrix selection surface genetic drift locomotion behavior transition rates Caenorhabditis elegans experimental evolution phenotypic stasis G-matrix selection surface genetic drift locomotion behavior transition rates Caenorhabditis elegans experimental evolution |
| title | Phenotypic stasis with genetic divergence
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| title_full | Phenotypic stasis with genetic divergence
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| title_fullStr | Phenotypic stasis with genetic divergence
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| title_full_unstemmed | Phenotypic stasis with genetic divergence
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| title_short | Phenotypic stasis with genetic divergence
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| title_sort | phenotypic stasis with genetic divergence |
| topic | phenotypic stasis G-matrix selection surface genetic drift locomotion behavior transition rates Caenorhabditis elegans experimental evolution phenotypic stasis G-matrix selection surface genetic drift locomotion behavior transition rates Caenorhabditis elegans experimental evolution phenotypic stasis G-matrix selection surface genetic drift locomotion behavior transition rates Caenorhabditis elegans experimental evolution |
| url | https://peercommunityjournal.org/articles/10.24072/pcjournal.349/ |
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