Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: case report and systematic review of literature
Hemophagocytic lymphohistiocytosis is a potentially fatal disorder resulting from excessive activation and non-malignant proliferation of T lymphocytes and macrophages. Neoplasms, autoimmune disorders and systemic infections can cause secondary hemophagocytic syndrome. The association of hemophagocy...
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| Format: | Article |
| Language: | English |
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The Journal of Infection in Developing Countries
2016-01-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/6385 |
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| author | Maria Scalzone Antonio Ruggiero Stefano Mastrangelo Giovanna Trombatore Vita Ridola Palma Maurizi Riccardo Riccardi |
| author_facet | Maria Scalzone Antonio Ruggiero Stefano Mastrangelo Giovanna Trombatore Vita Ridola Palma Maurizi Riccardo Riccardi |
| author_sort | Maria Scalzone |
| collection | DOAJ |
| description | Hemophagocytic lymphohistiocytosis is a potentially fatal disorder resulting from excessive activation and non-malignant proliferation of T lymphocytes and macrophages. Neoplasms, autoimmune disorders and systemic infections can cause secondary hemophagocytic syndrome. The association of hemophagocytic syndrome and visceral leishmaniasis is rarely found in childhood. We report a case of an infant affected by hemophagocytic lymphohistiocytosis secondary to visceral leishamniasis and describe all cases of hemophagocytic syndrome associated with visceral leishamniasis in childhood reported in literature, focusing on clinical manifestation, diagnosis and treatment.
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| format | Article |
| id | doaj-art-35fc2135d4bf48a889807ab59f2a408b |
| institution | DOAJ |
| issn | 1972-2680 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-35fc2135d4bf48a889807ab59f2a408b2025-08-20T02:57:04ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802016-01-01100110.3855/jidc.6385Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: case report and systematic review of literatureMaria Scalzone0Antonio Ruggiero1Stefano Mastrangelo2Giovanna Trombatore3Vita Ridola4Palma Maurizi5Riccardo Riccardi6Catholic University of Rome, Rome, ItalyCatholic University of Rome, Rome, ItalyCatholic University of Rome, Rome, ItalyCatholic University of Rome, Rome, ItalyCatholic University of Rome, Rome, ItalyCatholic University of Rome, Rome, ItalyCatholic University of Rome, Rome, ItalyHemophagocytic lymphohistiocytosis is a potentially fatal disorder resulting from excessive activation and non-malignant proliferation of T lymphocytes and macrophages. Neoplasms, autoimmune disorders and systemic infections can cause secondary hemophagocytic syndrome. The association of hemophagocytic syndrome and visceral leishmaniasis is rarely found in childhood. We report a case of an infant affected by hemophagocytic lymphohistiocytosis secondary to visceral leishamniasis and describe all cases of hemophagocytic syndrome associated with visceral leishamniasis in childhood reported in literature, focusing on clinical manifestation, diagnosis and treatment. https://jidc.org/index.php/journal/article/view/6385Hemophagocytic lymphohistiocytosisleishmaniachildhoodliposomal amphotericin B |
| spellingShingle | Maria Scalzone Antonio Ruggiero Stefano Mastrangelo Giovanna Trombatore Vita Ridola Palma Maurizi Riccardo Riccardi Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: case report and systematic review of literature Journal of Infection in Developing Countries Hemophagocytic lymphohistiocytosis leishmania childhood liposomal amphotericin B |
| title | Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: case report and systematic review of literature |
| title_full | Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: case report and systematic review of literature |
| title_fullStr | Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: case report and systematic review of literature |
| title_full_unstemmed | Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: case report and systematic review of literature |
| title_short | Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: case report and systematic review of literature |
| title_sort | hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children case report and systematic review of literature |
| topic | Hemophagocytic lymphohistiocytosis leishmania childhood liposomal amphotericin B |
| url | https://jidc.org/index.php/journal/article/view/6385 |
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