Effect of resveratrol on key signaling pathways including SIRT1/AMPK/Smad3/TGF-β and miRNA-141 related to NAFLD in an animal model

Effect of resveratrol on key signaling pathways including SIRT1/AMPK/Smad3/TGF-β and miRNA-141 related to NAFLD in an animal model

Background and purpose: Non-alcoholic fatty liver disease (NAFLD) is a chronic metabolic condition characterized by the accumulation of excess fat in the liver, which can ultimately lead to fibrosis and cirrhosis. This study investigated the impact of resveratrol on the signaling pathways miR-141/SI...

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Main Authors: Sahar Yarahmadi, Mohammadjavad Sotoudeheian, Navid Farahmandian, Yaser Mohammadi, Mehdi Koushki, Esmaeel Babaeenezhad, Zeynab Yousefi, Soudabeh Fallah
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-05-01
Series:Research in Pharmaceutical Sciences
Subjects:
mirna-141
non-alcoholic fatty liver disease
resveratrol
sirt1
tgf-β
Online Access:https://journals.lww.com/10.4103/RPS.RPS_220_24
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