Continuous Flow Controlled Synthesis of Gold Nanoparticles Using Pulsed Mixing Microfluidic System
To prepare the gold nanoparticles (AuNPs) with uniform sizes, fine morphology, and good monodispersity, a pulsed mixing microfluidic system based on PZT actuation was presented. The system includes PZT micropump and Y type micromixer. By adjusting voltage (entrance flow rate), pulsed frequency, phas...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Advances in Materials Science and Engineering |
| Online Access: | http://dx.doi.org/10.1155/2015/160819 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832567577182732288 |
|---|---|
| author | Guojun Liu Xuhao Yang Yan Li Zhigang Yang Wen Hong JianFang Liu |
| author_facet | Guojun Liu Xuhao Yang Yan Li Zhigang Yang Wen Hong JianFang Liu |
| author_sort | Guojun Liu |
| collection | DOAJ |
| description | To prepare the gold nanoparticles (AuNPs) with uniform sizes, fine morphology, and good monodispersity, a pulsed mixing microfluidic system based on PZT actuation was presented. The system includes PZT micropump and Y type micromixer. By adjusting voltage (entrance flow rate), pulsed frequency, phase, and other parameters, a variety of mixing modes can be achieved, so as to realize the controllable synthesis of nanoparticles in a certain range. By numerical simulation and analysis, the channel section size, entrance angle, and pulse frequency were optimized. Based on the optimized structure and working parameters, the test prototype has been manufactured in lab, and the related synthesis tests of AuNPs were carried out. The test results indicate that AuNPs with uniform morphology and good monodispersity can be synthesized using the system with the section size (0.4 mm × 0.4 mm), the entrance channel angle (60°) under condition of the pulsed frequency (300 Hz), and the entrance flow rate (4 mL/min). The average diameter and its standard deviation of AuNPs synthesized were 21.6 nm, 4.83 nm, respectively. The research work above can be applied to the fields such as the controlled synthesis of noble metal nanoparticles, biomedicine, and microchemical system. |
| format | Article |
| id | doaj-art-35dfca732b2f4f5caff8935406fd4177 |
| institution | Kabale University |
| issn | 1687-8434 1687-8442 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Materials Science and Engineering |
| spelling | doaj-art-35dfca732b2f4f5caff8935406fd41772025-02-03T01:01:08ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422015-01-01201510.1155/2015/160819160819Continuous Flow Controlled Synthesis of Gold Nanoparticles Using Pulsed Mixing Microfluidic SystemGuojun Liu0Xuhao Yang1Yan Li2Zhigang Yang3Wen Hong4JianFang Liu5College of Mechanical Science and Engineering, Jilin University, Changchun 130025, ChinaCollege of Mechanical Science and Engineering, Jilin University, Changchun 130025, ChinaDepartment of Emergency, China-Japan Union Hospital, Jilin University, Changchun 130033, ChinaCollege of Mechanical Science and Engineering, Jilin University, Changchun 130025, ChinaCollege of Mechanical Science and Engineering, Jilin University, Changchun 130025, ChinaCollege of Mechanical Science and Engineering, Jilin University, Changchun 130025, ChinaTo prepare the gold nanoparticles (AuNPs) with uniform sizes, fine morphology, and good monodispersity, a pulsed mixing microfluidic system based on PZT actuation was presented. The system includes PZT micropump and Y type micromixer. By adjusting voltage (entrance flow rate), pulsed frequency, phase, and other parameters, a variety of mixing modes can be achieved, so as to realize the controllable synthesis of nanoparticles in a certain range. By numerical simulation and analysis, the channel section size, entrance angle, and pulse frequency were optimized. Based on the optimized structure and working parameters, the test prototype has been manufactured in lab, and the related synthesis tests of AuNPs were carried out. The test results indicate that AuNPs with uniform morphology and good monodispersity can be synthesized using the system with the section size (0.4 mm × 0.4 mm), the entrance channel angle (60°) under condition of the pulsed frequency (300 Hz), and the entrance flow rate (4 mL/min). The average diameter and its standard deviation of AuNPs synthesized were 21.6 nm, 4.83 nm, respectively. The research work above can be applied to the fields such as the controlled synthesis of noble metal nanoparticles, biomedicine, and microchemical system.http://dx.doi.org/10.1155/2015/160819 |
| spellingShingle | Guojun Liu Xuhao Yang Yan Li Zhigang Yang Wen Hong JianFang Liu Continuous Flow Controlled Synthesis of Gold Nanoparticles Using Pulsed Mixing Microfluidic System Advances in Materials Science and Engineering |
| title | Continuous Flow Controlled Synthesis of Gold Nanoparticles Using Pulsed Mixing Microfluidic System |
| title_full | Continuous Flow Controlled Synthesis of Gold Nanoparticles Using Pulsed Mixing Microfluidic System |
| title_fullStr | Continuous Flow Controlled Synthesis of Gold Nanoparticles Using Pulsed Mixing Microfluidic System |
| title_full_unstemmed | Continuous Flow Controlled Synthesis of Gold Nanoparticles Using Pulsed Mixing Microfluidic System |
| title_short | Continuous Flow Controlled Synthesis of Gold Nanoparticles Using Pulsed Mixing Microfluidic System |
| title_sort | continuous flow controlled synthesis of gold nanoparticles using pulsed mixing microfluidic system |
| url | http://dx.doi.org/10.1155/2015/160819 |
| work_keys_str_mv | AT guojunliu continuousflowcontrolledsynthesisofgoldnanoparticlesusingpulsedmixingmicrofluidicsystem AT xuhaoyang continuousflowcontrolledsynthesisofgoldnanoparticlesusingpulsedmixingmicrofluidicsystem AT yanli continuousflowcontrolledsynthesisofgoldnanoparticlesusingpulsedmixingmicrofluidicsystem AT zhigangyang continuousflowcontrolledsynthesisofgoldnanoparticlesusingpulsedmixingmicrofluidicsystem AT wenhong continuousflowcontrolledsynthesisofgoldnanoparticlesusingpulsedmixingmicrofluidicsystem AT jianfangliu continuousflowcontrolledsynthesisofgoldnanoparticlesusingpulsedmixingmicrofluidicsystem |