Epidemiological investigation on correlations between metabolism syndrome and chronic kidney disease among unit workers in Zhongxiang city
Objective To investigate the correlation between metabolic syndrome(MS) and chronic kidney diseases(CKD) among Unit workers in Zhongxiang city.Methods 64 410 employees from fixed population of 102 fixed units in Zhongxiang city which had physical examination in our hospital during April 2012 to Janu...
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Editorial Department of Journal of Clinical Nephrology
2015-01-01
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| Series: | Linchuang shenzangbing zazhi |
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| author | LIAO Yan XUE Chen HE Cong CAO Ming-tang SUN Zhong DENG Xian-quan HUANG Fan LIU Jian-she |
| author_facet | LIAO Yan XUE Chen HE Cong CAO Ming-tang SUN Zhong DENG Xian-quan HUANG Fan LIU Jian-she |
| author_sort | LIAO Yan |
| collection | DOAJ |
| description | Objective To investigate the correlation between metabolic syndrome(MS) and chronic kidney diseases(CKD) among Unit workers in Zhongxiang city.Methods 64 410 employees from fixed population of 102 fixed units in Zhongxiang city which had physical examination in our hospital during April 2012 to January 2015 were collected using stratified multistage random cluster sampling.All investigation objects were interviewed(with or without smoking,drinking history and history of kidney) and given physical examination,including height,weight,waist circumference,hip circumference,systolic blood pressure(SBP),diastolic blood pressure(DBP),body mass index(BMI),glucose,lipids(TG,HDL-C,LDL-C),kidney function(SCr,UA),urine routine test(urine protein,urine occult blood),etc.Multi-element Logistic Regression analysis was utilized to study the risk factors of CKD by introducing individual components in the MS(central obesity,high blood pressure,high FPG,high TG,lower HDL-C,etc.).Results 64 410 subjects were enrolled in the study and completed the questionnaires.Approximately 12.2%(95%CI:7.6%~9.6%) of these subjects have at least one indicator of MS.Approximately 7.4%(4 766 cases of CKD,59 644 cases of nonCKD) subjects have faced CKD.There are 978 subjects(7.4%) faced CKD among MS patients.The difference between the prevalence of CKD in the non-MS patients(7.0%) and the prevalence rate of CKD in the MS patients(7.4%) is statistical significant(P=0.001).Low HDL-C,high FPG,high blood pressure,high blood pressure and high uric acid are all statistical significant(P<0.05).The value of OR(95%CI) are as follows,0.521(0.645~0.446),3.489(2.829~2.579),2.137(1.745~4.311),1.507(1.241~1.832),1.502(1.125~2.005).Conclusions The prevalence of CKD in the MS is significantly higher than it in the non-MS.And abnormal metabolic components,such as high blood pressure,high FPG,lower HDL-C,central obesity and high uric acid are the independent risk factors of CKD.It is crucial important to prevent and control the risk factors of MS in order to reduce prevalence of MS and CKD in the region. |
| format | Article |
| id | doaj-art-35c5fdb9fd0542ffb5fffac3e609bb37 |
| institution | Kabale University |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2015-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-35c5fdb9fd0542ffb5fffac3e609bb372025-08-20T03:48:58ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902015-01-0172973357919746Epidemiological investigation on correlations between metabolism syndrome and chronic kidney disease among unit workers in Zhongxiang cityLIAO YanXUE ChenHE CongCAO Ming-tangSUN ZhongDENG Xian-quanHUANG FanLIU Jian-sheObjective To investigate the correlation between metabolic syndrome(MS) and chronic kidney diseases(CKD) among Unit workers in Zhongxiang city.Methods 64 410 employees from fixed population of 102 fixed units in Zhongxiang city which had physical examination in our hospital during April 2012 to January 2015 were collected using stratified multistage random cluster sampling.All investigation objects were interviewed(with or without smoking,drinking history and history of kidney) and given physical examination,including height,weight,waist circumference,hip circumference,systolic blood pressure(SBP),diastolic blood pressure(DBP),body mass index(BMI),glucose,lipids(TG,HDL-C,LDL-C),kidney function(SCr,UA),urine routine test(urine protein,urine occult blood),etc.Multi-element Logistic Regression analysis was utilized to study the risk factors of CKD by introducing individual components in the MS(central obesity,high blood pressure,high FPG,high TG,lower HDL-C,etc.).Results 64 410 subjects were enrolled in the study and completed the questionnaires.Approximately 12.2%(95%CI:7.6%~9.6%) of these subjects have at least one indicator of MS.Approximately 7.4%(4 766 cases of CKD,59 644 cases of nonCKD) subjects have faced CKD.There are 978 subjects(7.4%) faced CKD among MS patients.The difference between the prevalence of CKD in the non-MS patients(7.0%) and the prevalence rate of CKD in the MS patients(7.4%) is statistical significant(P=0.001).Low HDL-C,high FPG,high blood pressure,high blood pressure and high uric acid are all statistical significant(P<0.05).The value of OR(95%CI) are as follows,0.521(0.645~0.446),3.489(2.829~2.579),2.137(1.745~4.311),1.507(1.241~1.832),1.502(1.125~2.005).Conclusions The prevalence of CKD in the MS is significantly higher than it in the non-MS.And abnormal metabolic components,such as high blood pressure,high FPG,lower HDL-C,central obesity and high uric acid are the independent risk factors of CKD.It is crucial important to prevent and control the risk factors of MS in order to reduce prevalence of MS and CKD in the region.http://www.lcszb.com/thesisDetails?columnId=57919746&Fpath=home&index=0Metabolic syndromeChronic kidney diseaseRisk factor |
| spellingShingle | LIAO Yan XUE Chen HE Cong CAO Ming-tang SUN Zhong DENG Xian-quan HUANG Fan LIU Jian-she Epidemiological investigation on correlations between metabolism syndrome and chronic kidney disease among unit workers in Zhongxiang city Linchuang shenzangbing zazhi Metabolic syndrome Chronic kidney disease Risk factor |
| title | Epidemiological investigation on correlations between metabolism syndrome and chronic kidney disease among unit workers in Zhongxiang city |
| title_full | Epidemiological investigation on correlations between metabolism syndrome and chronic kidney disease among unit workers in Zhongxiang city |
| title_fullStr | Epidemiological investigation on correlations between metabolism syndrome and chronic kidney disease among unit workers in Zhongxiang city |
| title_full_unstemmed | Epidemiological investigation on correlations between metabolism syndrome and chronic kidney disease among unit workers in Zhongxiang city |
| title_short | Epidemiological investigation on correlations between metabolism syndrome and chronic kidney disease among unit workers in Zhongxiang city |
| title_sort | epidemiological investigation on correlations between metabolism syndrome and chronic kidney disease among unit workers in zhongxiang city |
| topic | Metabolic syndrome Chronic kidney disease Risk factor |
| url | http://www.lcszb.com/thesisDetails?columnId=57919746&Fpath=home&index=0 |
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