Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial Interventions

This case report examines the unexpected increase in suicidal ideation following ketamine infusion therapy in a 75-year-old female with a history of treatment-resistant depression. Despite ketamine’s established efficacy in treating depression and acute suicidality, this patient’s condition deterior...

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Main Authors: Jai Ahuja, Luba Leontieva
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2024/2143372
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author Jai Ahuja
Luba Leontieva
author_facet Jai Ahuja
Luba Leontieva
author_sort Jai Ahuja
collection DOAJ
description This case report examines the unexpected increase in suicidal ideation following ketamine infusion therapy in a 75-year-old female with a history of treatment-resistant depression. Despite ketamine’s established efficacy in treating depression and acute suicidality, this patient’s condition deteriorated posttreatment. The report delves into the patient’s complex background, including psychosocial stressors, genetic predisposition to depression, and a history of personality traits that may have influenced her response to ketamine. This case underscores the importance of cautious administration of ketamine, especially in patients with personality disorders, and calls for deeper understanding and individualized treatment plans in mental health care. It is a reminder of the complexities involved in treating mental health conditions and the varying effects of treatments like ketamine on different individuals.
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spelling doaj-art-35c33e3fe18247cca702cb5412c26ab42025-02-03T01:29:25ZengWileyCase Reports in Psychiatry2090-68382024-01-01202410.1155/2024/2143372Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial InterventionsJai Ahuja0Luba Leontieva1Department of PsychiatryDepartment of PsychiatryThis case report examines the unexpected increase in suicidal ideation following ketamine infusion therapy in a 75-year-old female with a history of treatment-resistant depression. Despite ketamine’s established efficacy in treating depression and acute suicidality, this patient’s condition deteriorated posttreatment. The report delves into the patient’s complex background, including psychosocial stressors, genetic predisposition to depression, and a history of personality traits that may have influenced her response to ketamine. This case underscores the importance of cautious administration of ketamine, especially in patients with personality disorders, and calls for deeper understanding and individualized treatment plans in mental health care. It is a reminder of the complexities involved in treating mental health conditions and the varying effects of treatments like ketamine on different individuals.http://dx.doi.org/10.1155/2024/2143372
spellingShingle Jai Ahuja
Luba Leontieva
Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial Interventions
Case Reports in Psychiatry
title Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial Interventions
title_full Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial Interventions
title_fullStr Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial Interventions
title_full_unstemmed Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial Interventions
title_short Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial Interventions
title_sort ketamine therapy in complex cases a cautionary tale of exacerbated personality traits and the crucial role of comprehensive follow up and psychosocial interventions
url http://dx.doi.org/10.1155/2024/2143372
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