Deubiquitinase Ubiquitin‐Specific Protease 29 Ameliorates Pathological Cardiac Hypertrophy through Inhibiting Transforming Growth Factor β‐Activated Kinase 1

Deubiquitinase Ubiquitin‐Specific Protease 29 Ameliorates Pathological Cardiac Hypertrophy through Inhibiting Transforming Growth Factor β‐Activated Kinase 1

Background Pathological cardiac hypertrophy, characterized by the involvement of multiple regulators, ultimately leads to heart failure in the absence of effective interventions. The identification of key factors involved is crucial for exploring novel treatments for heart failure. However, the func...

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Bibliographic Details
Main Authors: Xi Jiang, Yan Sun, Hongjie Shi, Zhen Liu, Jianqing Zhang, Changlu Xu, Yufeng Hu, Tiesheng Niu
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
deubiquitination
pathological cardiac hypertrophy
TAK1
USP29
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.034962
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