Role of Surgery in Vestibular Schwannoma following prior Stereotactic Radiosurgery

Stereotactic radiosurgery (SRS) is widely used for treating vestibular schwannoma (VS), offering high tumour control rates, especially in small to medium-sized tumours. However, a subset of patients experiences SRS failure, requiring subsequent salvage microsurgery (MS). The primary reason for salv...

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Main Authors: Zanib Javed, Muhammad Shahzad Shamim
Format: Article
Language:English
Published: Pakistan Medical Association 2024-09-01
Series:Journal of the Pakistan Medical Association
Online Access:https://jpma.org.pk/index.php/public_html/article/view/22307
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author Zanib Javed
Muhammad Shahzad Shamim
author_facet Zanib Javed
Muhammad Shahzad Shamim
author_sort Zanib Javed
collection DOAJ
description Stereotactic radiosurgery (SRS) is widely used for treating vestibular schwannoma (VS), offering high tumour control rates, especially in small to medium-sized tumours. However, a subset of patients experiences SRS failure, requiring subsequent salvage microsurgery (MS). The primary reason for salvage surgery is continued tumour growth, but other causes include symptom progression and cystic enlargement. Salvage surgery is more challenging due to increased tumour adhesion to critical structures, resulting in higher complication rates, particularly for facial nerve preservation. Studies suggest subtotal resection may offer better outcomes than gross total resection in terms of facial nerve function, though treatment remains complex and outcomes vary. Keywords: Vestibular schwannoma, stereotactic radiosurgery, salvage surgery, facial nerve.
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series Journal of the Pakistan Medical Association
spelling doaj-art-35bb68b7663142ceb4668e9c3585abd92025-08-20T02:41:24ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822024-09-01741010.47391/JPMA.24-84Role of Surgery in Vestibular Schwannoma following prior Stereotactic RadiosurgeryZanib Javed0Muhammad Shahzad Shamim1Department of Neurosurgery, Aga Khan University Hospital, KarachiDepartment of Neurosurgery, Aga Khan University Hospital, Karachi Stereotactic radiosurgery (SRS) is widely used for treating vestibular schwannoma (VS), offering high tumour control rates, especially in small to medium-sized tumours. However, a subset of patients experiences SRS failure, requiring subsequent salvage microsurgery (MS). The primary reason for salvage surgery is continued tumour growth, but other causes include symptom progression and cystic enlargement. Salvage surgery is more challenging due to increased tumour adhesion to critical structures, resulting in higher complication rates, particularly for facial nerve preservation. Studies suggest subtotal resection may offer better outcomes than gross total resection in terms of facial nerve function, though treatment remains complex and outcomes vary. Keywords: Vestibular schwannoma, stereotactic radiosurgery, salvage surgery, facial nerve. https://jpma.org.pk/index.php/public_html/article/view/22307
spellingShingle Zanib Javed
Muhammad Shahzad Shamim
Role of Surgery in Vestibular Schwannoma following prior Stereotactic Radiosurgery
Journal of the Pakistan Medical Association
title Role of Surgery in Vestibular Schwannoma following prior Stereotactic Radiosurgery
title_full Role of Surgery in Vestibular Schwannoma following prior Stereotactic Radiosurgery
title_fullStr Role of Surgery in Vestibular Schwannoma following prior Stereotactic Radiosurgery
title_full_unstemmed Role of Surgery in Vestibular Schwannoma following prior Stereotactic Radiosurgery
title_short Role of Surgery in Vestibular Schwannoma following prior Stereotactic Radiosurgery
title_sort role of surgery in vestibular schwannoma following prior stereotactic radiosurgery
url https://jpma.org.pk/index.php/public_html/article/view/22307
work_keys_str_mv AT zanibjaved roleofsurgeryinvestibularschwannomafollowingpriorstereotacticradiosurgery
AT muhammadshahzadshamim roleofsurgeryinvestibularschwannomafollowingpriorstereotacticradiosurgery