Development of Spectrophotometric method for quantitative determination of dexamethasone in pharmaceutical preparations
This Study is concerned a fast, easy, sensitive, accurate and economical spectrophotometric method for the determination of Dexamethasone. This method based on the use of UV- spectra measurements at 242 nm. The linearity of the method is performed between (3 - 65) μg.ml-1, the coefficient of ...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tikrit University
2023-01-01
|
| Series: | Tikrit Journal of Pure Science |
| Subjects: | |
| Online Access: | https://tjpsj.org/index.php/tjps/article/view/777 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849704165297618944 |
|---|---|
| author | Rafal Abdulraheem Abdullah Khalaf F. AL-Samarraee |
| author_facet | Rafal Abdulraheem Abdullah Khalaf F. AL-Samarraee |
| author_sort | Rafal Abdulraheem Abdullah |
| collection | DOAJ |
| description |
This Study is concerned a fast, easy, sensitive, accurate and economical spectrophotometric method for the determination of Dexamethasone. This method based on the use of UV- spectra measurements at 242 nm.
The linearity of the method is performed between (3 - 65) μg.ml-1, the coefficient of correlation was = 0.9998. The value of Rec% and RSD% are found at the range (95.28 -102.86)% and (0 - 0.272 )% respectively, The LOD and LOQ were (0.024and 0.081) μg.ml-1, respectively .
The method was successfully applied to the determination of DMT in Bulk and pharmaceutical preparations
|
| format | Article |
| id | doaj-art-35b0b0d410ad49f2aa0ac5b1b730e8dd |
| institution | DOAJ |
| issn | 1813-1662 2415-1726 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Tikrit University |
| record_format | Article |
| series | Tikrit Journal of Pure Science |
| spelling | doaj-art-35b0b0d410ad49f2aa0ac5b1b730e8dd2025-08-20T03:16:51ZengTikrit UniversityTikrit Journal of Pure Science1813-16622415-17262023-01-0122510.25130/tjps.v22i5.777Development of Spectrophotometric method for quantitative determination of dexamethasone in pharmaceutical preparationsRafal Abdulraheem AbdullahKhalaf F. AL-Samarraee This Study is concerned a fast, easy, sensitive, accurate and economical spectrophotometric method for the determination of Dexamethasone. This method based on the use of UV- spectra measurements at 242 nm. The linearity of the method is performed between (3 - 65) μg.ml-1, the coefficient of correlation was = 0.9998. The value of Rec% and RSD% are found at the range (95.28 -102.86)% and (0 - 0.272 )% respectively, The LOD and LOQ were (0.024and 0.081) μg.ml-1, respectively . The method was successfully applied to the determination of DMT in Bulk and pharmaceutical preparations https://tjpsj.org/index.php/tjps/article/view/777Spectrophotometric methoddexamethasonepharmaceutical preparations |
| spellingShingle | Rafal Abdulraheem Abdullah Khalaf F. AL-Samarraee Development of Spectrophotometric method for quantitative determination of dexamethasone in pharmaceutical preparations Tikrit Journal of Pure Science Spectrophotometric method dexamethasone pharmaceutical preparations |
| title | Development of Spectrophotometric method for quantitative determination of dexamethasone in pharmaceutical preparations |
| title_full | Development of Spectrophotometric method for quantitative determination of dexamethasone in pharmaceutical preparations |
| title_fullStr | Development of Spectrophotometric method for quantitative determination of dexamethasone in pharmaceutical preparations |
| title_full_unstemmed | Development of Spectrophotometric method for quantitative determination of dexamethasone in pharmaceutical preparations |
| title_short | Development of Spectrophotometric method for quantitative determination of dexamethasone in pharmaceutical preparations |
| title_sort | development of spectrophotometric method for quantitative determination of dexamethasone in pharmaceutical preparations |
| topic | Spectrophotometric method dexamethasone pharmaceutical preparations |
| url | https://tjpsj.org/index.php/tjps/article/view/777 |
| work_keys_str_mv | AT rafalabdulraheemabdullah developmentofspectrophotometricmethodforquantitativedeterminationofdexamethasoneinpharmaceuticalpreparations AT khalaffalsamarraee developmentofspectrophotometricmethodforquantitativedeterminationofdexamethasoneinpharmaceuticalpreparations |