Infectious and Noninfectious Granulomatosis in Patient with Multiple Sclerosis: Diagnostic Dilemmas and Followup
Patient was followed up over the course of 30 years. In 1978, after severe systemic infection followed by fever, pulmonary edema, and numerous neurological manifestations, patient was differentially diagnosed with apoplectic form of multiple sclerosis (MS), which was confirmed a year later via neuro...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Immunology |
| Online Access: | http://dx.doi.org/10.1155/2014/876525 |
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| _version_ | 1832551523110879232 |
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| author | Jelena Paovic Predrag Paovic Vojislav Sredovic |
| author_facet | Jelena Paovic Predrag Paovic Vojislav Sredovic |
| author_sort | Jelena Paovic |
| collection | DOAJ |
| description | Patient was followed up over the course of 30 years. In 1978, after severe systemic infection followed by fever, pulmonary edema, and numerous neurological manifestations, patient was differentially diagnosed with apoplectic form of multiple sclerosis (MS), which was confirmed a year later via neurological and MRI findings. Approximately 20 years following the initial attack, sarcoidosis was diagnosed during the regular preoperative procedures required for cataract surgery. As consequence of lower immune system, infectious granulomatosis in form of pulmonary tuberculosis developed. Ophthalmological findings revealed bilateral retrobulbar neuritis (RBN) approximately six years after initial attack. This developed into total uveitis with retinal periphlebitis and anterior granulomatous uveitis—all of which are clinically similar in both MS and sarcoidosis. |
| format | Article |
| id | doaj-art-35ab1625c24e401db931b22bdddf9ec8 |
| institution | Kabale University |
| issn | 2090-6609 2090-6617 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Immunology |
| spelling | doaj-art-35ab1625c24e401db931b22bdddf9ec82025-02-03T06:01:11ZengWileyCase Reports in Immunology2090-66092090-66172014-01-01201410.1155/2014/876525876525Infectious and Noninfectious Granulomatosis in Patient with Multiple Sclerosis: Diagnostic Dilemmas and FollowupJelena Paovic0Predrag Paovic1Vojislav Sredovic2University Eye Clinic, Clinical Center of Serbia, Pasterova 2, 11000 Belgrade, SerbiaUniversity Eye Clinic, Clinical Center of Serbia, Pasterova 2, 11000 Belgrade, SerbiaPrimary Health Care Center, Jove Negusevica 5, 22140 Pecinci, SerbiaPatient was followed up over the course of 30 years. In 1978, after severe systemic infection followed by fever, pulmonary edema, and numerous neurological manifestations, patient was differentially diagnosed with apoplectic form of multiple sclerosis (MS), which was confirmed a year later via neurological and MRI findings. Approximately 20 years following the initial attack, sarcoidosis was diagnosed during the regular preoperative procedures required for cataract surgery. As consequence of lower immune system, infectious granulomatosis in form of pulmonary tuberculosis developed. Ophthalmological findings revealed bilateral retrobulbar neuritis (RBN) approximately six years after initial attack. This developed into total uveitis with retinal periphlebitis and anterior granulomatous uveitis—all of which are clinically similar in both MS and sarcoidosis.http://dx.doi.org/10.1155/2014/876525 |
| spellingShingle | Jelena Paovic Predrag Paovic Vojislav Sredovic Infectious and Noninfectious Granulomatosis in Patient with Multiple Sclerosis: Diagnostic Dilemmas and Followup Case Reports in Immunology |
| title | Infectious and Noninfectious Granulomatosis in Patient with Multiple Sclerosis: Diagnostic Dilemmas and Followup |
| title_full | Infectious and Noninfectious Granulomatosis in Patient with Multiple Sclerosis: Diagnostic Dilemmas and Followup |
| title_fullStr | Infectious and Noninfectious Granulomatosis in Patient with Multiple Sclerosis: Diagnostic Dilemmas and Followup |
| title_full_unstemmed | Infectious and Noninfectious Granulomatosis in Patient with Multiple Sclerosis: Diagnostic Dilemmas and Followup |
| title_short | Infectious and Noninfectious Granulomatosis in Patient with Multiple Sclerosis: Diagnostic Dilemmas and Followup |
| title_sort | infectious and noninfectious granulomatosis in patient with multiple sclerosis diagnostic dilemmas and followup |
| url | http://dx.doi.org/10.1155/2014/876525 |
| work_keys_str_mv | AT jelenapaovic infectiousandnoninfectiousgranulomatosisinpatientwithmultiplesclerosisdiagnosticdilemmasandfollowup AT predragpaovic infectiousandnoninfectiousgranulomatosisinpatientwithmultiplesclerosisdiagnosticdilemmasandfollowup AT vojislavsredovic infectiousandnoninfectiousgranulomatosisinpatientwithmultiplesclerosisdiagnosticdilemmasandfollowup |