Impacts of fishmeal replacement with peanut meal on growth, antioxidant capacity, digestive enzyme activity and protein metabolism-related gene expression in swimming crab Portunus trituberculatus

To assess the effects of fishmeal (FM) replacement with peanut meal (PM) on growth performance, antioxidative capacity and the expression of genes associated with protein metabolism and inflammation in Portunus trituberculatus, a 56-day feeding trial was conducted. The basal diet (PM0) comprised 30 ...

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Main Authors: Xishuai Cui, Hongyu Peng, Tingting Zhu, Yao Deng, Shichao Xie, Wenhao Zhan, Peng Sun, Tiantian Xu, Haiqing Cao, Zheng Tang, Min Jin, Qicun Zhou
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Aquaculture Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352513425003229
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author Xishuai Cui
Hongyu Peng
Tingting Zhu
Yao Deng
Shichao Xie
Wenhao Zhan
Peng Sun
Tiantian Xu
Haiqing Cao
Zheng Tang
Min Jin
Qicun Zhou
author_facet Xishuai Cui
Hongyu Peng
Tingting Zhu
Yao Deng
Shichao Xie
Wenhao Zhan
Peng Sun
Tiantian Xu
Haiqing Cao
Zheng Tang
Min Jin
Qicun Zhou
author_sort Xishuai Cui
collection DOAJ
description To assess the effects of fishmeal (FM) replacement with peanut meal (PM) on growth performance, antioxidative capacity and the expression of genes associated with protein metabolism and inflammation in Portunus trituberculatus, a 56-day feeding trial was conducted. The basal diet (PM0) comprised 30 % FM, while the experimental diets were formulated by replacing fishmeal with peanut meal at 10 % (PM10), 20 % (PM20), 30 % (PM30), and 40 % (PM40) substitution levels, respectively. The results revealed that 30 % and 40 % FM replacement with PM markedly reduced PWG. Crabs fed PM30 and PM40 diets exhibited significantly lower activities of pepsin and trypsin in hepatopancreas compared to other treatments, while the highest Na⁺, K⁺-ATPase activity was recorded in crabs fed diet PM20. Crabs fed PM20 diet showed higher T-SOD, T-AOC and nitric oxide activities in the hemolymph than those fed others. The expression of 4e-bp1, a gene associated with the TOR signaling pathway, was markedly up-regulated in the hepatopancreas of crabs fed PM30 and PM40 diets, whereas tor expression in muscle was down-regulated with increasing FM replacement. Furthermore, gpx and cat expression in the hepatopancreas was markedly down-regulated, while myd88 and tlr4 expression in the intestine was up-regulated in crabs fed 30 % and 40 % replacement diets. In summary, the optimal replacement level of fishmeal (FM) with peanut meal (PM) was 20.05 %, while replacements exceeding 30 % suppressed growth and impaired protein metabolism.
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spelling doaj-art-35a9537e650c4fa8ae0ca46a706ad5992025-08-20T03:45:12ZengElsevierAquaculture Reports2352-51342025-09-014310293610.1016/j.aqrep.2025.102936Impacts of fishmeal replacement with peanut meal on growth, antioxidant capacity, digestive enzyme activity and protein metabolism-related gene expression in swimming crab Portunus trituberculatusXishuai Cui0Hongyu Peng1Tingting Zhu2Yao Deng3Shichao Xie4Wenhao Zhan5Peng Sun6Tiantian Xu7Haiqing Cao8Zheng Tang9Min Jin10Qicun Zhou11Laboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, ChinaLaboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, China; Corresponding authors at: Laboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China.Laboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China; Key Laboratory of Aquaculture Biotechnology Ministry of Education, Ningbo University, Ningbo 315211, China; Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture, Ningbo 315211, China; Key Laboratory of Green Mariculture (Co-construction by Ministry and Province), Ministry of Agriculture and Rural, Ningbo 315211, China; Corresponding authors at: Laboratory of Fish and Shellfish Nutrition, School of Marine Sciences, Ningbo University, Ningbo 315211, China.To assess the effects of fishmeal (FM) replacement with peanut meal (PM) on growth performance, antioxidative capacity and the expression of genes associated with protein metabolism and inflammation in Portunus trituberculatus, a 56-day feeding trial was conducted. The basal diet (PM0) comprised 30 % FM, while the experimental diets were formulated by replacing fishmeal with peanut meal at 10 % (PM10), 20 % (PM20), 30 % (PM30), and 40 % (PM40) substitution levels, respectively. The results revealed that 30 % and 40 % FM replacement with PM markedly reduced PWG. Crabs fed PM30 and PM40 diets exhibited significantly lower activities of pepsin and trypsin in hepatopancreas compared to other treatments, while the highest Na⁺, K⁺-ATPase activity was recorded in crabs fed diet PM20. Crabs fed PM20 diet showed higher T-SOD, T-AOC and nitric oxide activities in the hemolymph than those fed others. The expression of 4e-bp1, a gene associated with the TOR signaling pathway, was markedly up-regulated in the hepatopancreas of crabs fed PM30 and PM40 diets, whereas tor expression in muscle was down-regulated with increasing FM replacement. Furthermore, gpx and cat expression in the hepatopancreas was markedly down-regulated, while myd88 and tlr4 expression in the intestine was up-regulated in crabs fed 30 % and 40 % replacement diets. In summary, the optimal replacement level of fishmeal (FM) with peanut meal (PM) was 20.05 %, while replacements exceeding 30 % suppressed growth and impaired protein metabolism.http://www.sciencedirect.com/science/article/pii/S2352513425003229Portunus trituberculatusPeanut mealGrowthProtein metabolismAntioxidant capacity
spellingShingle Xishuai Cui
Hongyu Peng
Tingting Zhu
Yao Deng
Shichao Xie
Wenhao Zhan
Peng Sun
Tiantian Xu
Haiqing Cao
Zheng Tang
Min Jin
Qicun Zhou
Impacts of fishmeal replacement with peanut meal on growth, antioxidant capacity, digestive enzyme activity and protein metabolism-related gene expression in swimming crab Portunus trituberculatus
Aquaculture Reports
Portunus trituberculatus
Peanut meal
Growth
Protein metabolism
Antioxidant capacity
title Impacts of fishmeal replacement with peanut meal on growth, antioxidant capacity, digestive enzyme activity and protein metabolism-related gene expression in swimming crab Portunus trituberculatus
title_full Impacts of fishmeal replacement with peanut meal on growth, antioxidant capacity, digestive enzyme activity and protein metabolism-related gene expression in swimming crab Portunus trituberculatus
title_fullStr Impacts of fishmeal replacement with peanut meal on growth, antioxidant capacity, digestive enzyme activity and protein metabolism-related gene expression in swimming crab Portunus trituberculatus
title_full_unstemmed Impacts of fishmeal replacement with peanut meal on growth, antioxidant capacity, digestive enzyme activity and protein metabolism-related gene expression in swimming crab Portunus trituberculatus
title_short Impacts of fishmeal replacement with peanut meal on growth, antioxidant capacity, digestive enzyme activity and protein metabolism-related gene expression in swimming crab Portunus trituberculatus
title_sort impacts of fishmeal replacement with peanut meal on growth antioxidant capacity digestive enzyme activity and protein metabolism related gene expression in swimming crab portunus trituberculatus
topic Portunus trituberculatus
Peanut meal
Growth
Protein metabolism
Antioxidant capacity
url http://www.sciencedirect.com/science/article/pii/S2352513425003229
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