Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro

Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro

Abstract Background Macrophages play an important role in the pathogenesis of ulcerative colitis (UC). We will explore the effects of sodium butyrate (SB) on macrophage function. Methods The targets of butyric acid were identified using SwissTargetPrediction database and surface plasmon resonance (S...

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Bibliographic Details
Main Authors: Miao Liu, Wen-jie Xie, Xu Zhang, Wei Wu, Guang Li, Lu Wang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Medicine
Subjects:
Sodium butyrate
Macrophage polarization
TGR5
β-arrestin2
Online Access:https://doi.org/10.1186/s10020-025-01096-7
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