Prehospital Medication Administration: A Randomised Study Comparing Intranasal and Intravenous Routes
Introduction. Opioid overdose is an ever-increasing problem globally. Recent studies have demonstrated that intranasal (IN) naloxone is a safe and effective alternative to traditional routes of naloxone administration for reversal of opioid overdose. Aims. This randomised controlled trial aimed to c...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Emergency Medicine International |
| Online Access: | http://dx.doi.org/10.1155/2012/476161 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850157606014812160 |
|---|---|
| author | Cian McDermott Niamh C. Collins |
| author_facet | Cian McDermott Niamh C. Collins |
| author_sort | Cian McDermott |
| collection | DOAJ |
| description | Introduction. Opioid overdose is an ever-increasing problem globally. Recent studies have demonstrated that intranasal (IN) naloxone is a safe and effective alternative to traditional routes of naloxone administration for reversal of opioid overdose. Aims. This randomised controlled trial aimed to compare the time taken to deliver intranasal medication with that of intravenous (IV) medication by advanced paramedic trainees. Methods. 18 advanced paramedic trainees administered either an IN or IV medication to a mannequin model in a classroom-based setting. The time taken for medication delivery was compared. End-user satisfaction was assessed using a 5-point questionnaire regarding ease of use and safety for both routes. Results.
The mean time taken for the IN and IV group was 87.1 seconds and 178.2 seconds respectively. The difference in mean time taken was 91.1 seconds (95% confidence interval 55.2 seconds to 126.9 seconds, P≤0.0001). 89% of advanced paramedic trainees reported that the IN route was easier and safer to use than the IV route. Conclusion. This study demonstrates that, amongst advanced paramedic trainees, the IN route of medication administration is significantly faster, better accepted and perceived to be safer than using the IV route. Thus, IN medication administration could be considered more frequently when administering emergency medications in a pre-hospital setting. |
| format | Article |
| id | doaj-art-358e25bf2a154f08a63e4c0fb3157a1b |
| institution | OA Journals |
| issn | 2090-2840 2090-2859 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Emergency Medicine International |
| spelling | doaj-art-358e25bf2a154f08a63e4c0fb3157a1b2025-08-20T02:24:07ZengWileyEmergency Medicine International2090-28402090-28592012-01-01201210.1155/2012/476161476161Prehospital Medication Administration: A Randomised Study Comparing Intranasal and Intravenous RoutesCian McDermott0Niamh C. Collins1Centre for Emergency Medical Science, University College Dublin, Dublin, IrelandMedical Advisory Group of the Pre-hospital Emergency Care Council in Ireland, Naas, IrelandIntroduction. Opioid overdose is an ever-increasing problem globally. Recent studies have demonstrated that intranasal (IN) naloxone is a safe and effective alternative to traditional routes of naloxone administration for reversal of opioid overdose. Aims. This randomised controlled trial aimed to compare the time taken to deliver intranasal medication with that of intravenous (IV) medication by advanced paramedic trainees. Methods. 18 advanced paramedic trainees administered either an IN or IV medication to a mannequin model in a classroom-based setting. The time taken for medication delivery was compared. End-user satisfaction was assessed using a 5-point questionnaire regarding ease of use and safety for both routes. Results. The mean time taken for the IN and IV group was 87.1 seconds and 178.2 seconds respectively. The difference in mean time taken was 91.1 seconds (95% confidence interval 55.2 seconds to 126.9 seconds, P≤0.0001). 89% of advanced paramedic trainees reported that the IN route was easier and safer to use than the IV route. Conclusion. This study demonstrates that, amongst advanced paramedic trainees, the IN route of medication administration is significantly faster, better accepted and perceived to be safer than using the IV route. Thus, IN medication administration could be considered more frequently when administering emergency medications in a pre-hospital setting.http://dx.doi.org/10.1155/2012/476161 |
| spellingShingle | Cian McDermott Niamh C. Collins Prehospital Medication Administration: A Randomised Study Comparing Intranasal and Intravenous Routes Emergency Medicine International |
| title | Prehospital Medication Administration: A Randomised Study Comparing Intranasal and Intravenous Routes |
| title_full | Prehospital Medication Administration: A Randomised Study Comparing Intranasal and Intravenous Routes |
| title_fullStr | Prehospital Medication Administration: A Randomised Study Comparing Intranasal and Intravenous Routes |
| title_full_unstemmed | Prehospital Medication Administration: A Randomised Study Comparing Intranasal and Intravenous Routes |
| title_short | Prehospital Medication Administration: A Randomised Study Comparing Intranasal and Intravenous Routes |
| title_sort | prehospital medication administration a randomised study comparing intranasal and intravenous routes |
| url | http://dx.doi.org/10.1155/2012/476161 |
| work_keys_str_mv | AT cianmcdermott prehospitalmedicationadministrationarandomisedstudycomparingintranasalandintravenousroutes AT niamhccollins prehospitalmedicationadministrationarandomisedstudycomparingintranasalandintravenousroutes |