A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma (“the Bad Kind” of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case Report
Verrucous carcinoma (also known as Ackerman tumor) is an uncommon exophytic low-grade well-differentiated variant of squamous cell carcinoma. This neoplasm typically involves the oral cavity, larynx, genitalia, skin, and esophagus. It is well known for its locally aggressiveness and for its clinical...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Skin Cancer |
| Online Access: | http://dx.doi.org/10.1155/2011/370605 |
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| author | A. Santoro G. Pannone M. Contaldo F. Sanguedolce V. Esposito R. Serpico L. Lo Muzio S. Papagerakis P. Bufo |
| author_facet | A. Santoro G. Pannone M. Contaldo F. Sanguedolce V. Esposito R. Serpico L. Lo Muzio S. Papagerakis P. Bufo |
| author_sort | A. Santoro |
| collection | DOAJ |
| description | Verrucous carcinoma (also known as Ackerman tumor) is an uncommon exophytic low-grade well-differentiated variant of squamous cell carcinoma. This neoplasm typically involves the oral cavity, larynx, genitalia, skin, and esophagus. It is well known for its locally aggressiveness and for its clinically slow-growing behaviour with minimal metastatic potential. Verrucous carcinoma of oral cavity is so closely aligned with the use of snuff and chewing tobacco that it has been called the “snuff dipper's cancer”. Recent studies have proved the role of HPV. The typical clinical presentation of oral verrucous carcinoma has long been known, as its remarkably innocuous appearance and biological behaviour. In this work, we report a review of the scientific literature and describe a troublesome case of oral verrucous cancer. |
| format | Article |
| id | doaj-art-3589a8fa9e7b4f578f6f7f7ea391b7f6 |
| institution | OA Journals |
| issn | 2090-2905 2090-2913 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Skin Cancer |
| spelling | doaj-art-3589a8fa9e7b4f578f6f7f7ea391b7f62025-08-20T02:24:07ZengWileyJournal of Skin Cancer2090-29052090-29132011-01-01201110.1155/2011/370605370605A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma (“the Bad Kind” of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case ReportA. Santoro0G. Pannone1M. Contaldo2F. Sanguedolce3V. Esposito4R. Serpico5L. Lo Muzio6S. Papagerakis7P. Bufo8Section of Anatomic Pathology and Cytopathology, Department of Surgical Sciences, University of Foggia, Viale L Pinto 1, 71100 Foggia, ItalySection of Anatomic Pathology and Cytopathology, Department of Surgical Sciences, University of Foggia, Viale L Pinto 1, 71100 Foggia, ItalyDepartment of Odontostomatological, Orthodontical and Surgical Sciences, Second University of Naples, Via De Crecchio 1, 80138 Naples, ItalySection of Anatomic Pathology and Cytopathology, Department of Surgical Sciences, University of Foggia, Viale L Pinto 1, 71100 Foggia, ItalyDepartment of Odontostomatological, Orthodontical and Surgical Sciences, Second University of Naples, Via De Crecchio 1, 80138 Naples, ItalyDepartment of Odontostomatological, Orthodontical and Surgical Sciences, Second University of Naples, Via De Crecchio 1, 80138 Naples, ItalySection of Oral Pathology, University of Foggia, Viale L Pinto 1, 71100 Foggia, ItalyDivision of Head and Neck Surgery and Oncology, Department of Otolaryngology, University of Michigan Medical School, Ann Arbor, MI 48109, USASection of Anatomic Pathology and Cytopathology, Department of Surgical Sciences, University of Foggia, Viale L Pinto 1, 71100 Foggia, ItalyVerrucous carcinoma (also known as Ackerman tumor) is an uncommon exophytic low-grade well-differentiated variant of squamous cell carcinoma. This neoplasm typically involves the oral cavity, larynx, genitalia, skin, and esophagus. It is well known for its locally aggressiveness and for its clinically slow-growing behaviour with minimal metastatic potential. Verrucous carcinoma of oral cavity is so closely aligned with the use of snuff and chewing tobacco that it has been called the “snuff dipper's cancer”. Recent studies have proved the role of HPV. The typical clinical presentation of oral verrucous carcinoma has long been known, as its remarkably innocuous appearance and biological behaviour. In this work, we report a review of the scientific literature and describe a troublesome case of oral verrucous cancer.http://dx.doi.org/10.1155/2011/370605 |
| spellingShingle | A. Santoro G. Pannone M. Contaldo F. Sanguedolce V. Esposito R. Serpico L. Lo Muzio S. Papagerakis P. Bufo A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma (“the Bad Kind” of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case Report Journal of Skin Cancer |
| title | A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma (“the Bad Kind” of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case Report |
| title_full | A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma (“the Bad Kind” of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case Report |
| title_fullStr | A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma (“the Bad Kind” of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case Report |
| title_full_unstemmed | A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma (“the Bad Kind” of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case Report |
| title_short | A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma (“the Bad Kind” of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case Report |
| title_sort | troubling diagnosis of verrucous squamous cell carcinoma the bad kind of keratosis and the need of clinical and pathological correlations a review of the literature with a case report |
| url | http://dx.doi.org/10.1155/2011/370605 |
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