Mitochondrial diseases caused by toxic compound accumulation: from etiopathology to therapeutic approaches

Abstract Mitochondrial disorders are a group of highly invalidating human conditions for which effective treatment is currently unavailable and characterized by faulty energy supply due to defective oxidative phosphorylation (OXPHOS). Given the complexity of mitochondrial genetics and biochemistry,...

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Bibliographic Details
Main Authors: Ivano Di Meo, Costanza Lamperti, Valeria Tiranti
Format: Article
Language:English
Published: Springer Nature 2015-07-01
Series:EMBO Molecular Medicine
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Online Access:https://doi.org/10.15252/emmm.201505040
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