Proteomic Profiling Reveals TPR and FGA as Predictive Serum Biomarkers of Relapse to First- and Second-Generation EGFR-TKIs in Advanced Lung Adenocarcinoma

Proteomic Profiling Reveals TPR and FGA as Predictive Serum Biomarkers of Relapse to First- and Second-Generation EGFR-TKIs in Advanced Lung Adenocarcinoma

<b>Background</b>: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) significantly enhance the median survival of patients with lung adenocarcinoma (ADC) that harbor EGFR-sensitive mutations. However, most patients inevitably experience tumor relapse owing to drug r...

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Bibliographic Details
Main Authors: Pritsana Raungrut, Wararat Chiangjong, Thipphanet Masjon, Saowanee Maungchanburi, Thidarat Ruklert, Narongwit Nakwan
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
TPR
FGA
serum biomarkers
relapse
EGFR-TKIs
proteomic
Online Access:https://www.mdpi.com/2227-9059/13/7/1608
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