Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the Literature
Ependymomas are common spinal lesions, with the vast majority arising in an intramedullary location. Several cases have been described in the literature of ependymomas in an intradural, extramedullary location. The authors present a case of a 56-year-old female who presented with several weeks of lo...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2016/3534791 |
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| author | Gene M. Weinstein Knarik Arkun James Kryzanski Michael Lanfranchi Gaurav K. Gupta Harprit Bedi |
| author_facet | Gene M. Weinstein Knarik Arkun James Kryzanski Michael Lanfranchi Gaurav K. Gupta Harprit Bedi |
| author_sort | Gene M. Weinstein |
| collection | DOAJ |
| description | Ependymomas are common spinal lesions, with the vast majority arising in an intramedullary location. Several cases have been described in the literature of ependymomas in an intradural, extramedullary location. The authors present a case of a 56-year-old female who presented with several weeks of lower back pain and weakness. MRI revealed an intradural, extramedullary enhancing mass at L1-L2. The mass was successfully resected surgically. Pathologic evaluation revealed a low grade glioma with components of both ependymoma and pilocytic astrocytoma with MUTYH G382D mutation. Extramedullary ependymomas are very rare tumors. To the authors’ knowledge, this is the first case of ependymoma/astrocytoma collision tumors described in an extramedullary location. |
| format | Article |
| id | doaj-art-357e11080b7146dc96dd353924c8eb5c |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-357e11080b7146dc96dd353924c8eb5c2025-02-03T05:52:06ZengWileyCase Reports in Pathology2090-67812090-679X2016-01-01201610.1155/2016/35347913534791Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the LiteratureGene M. Weinstein0Knarik Arkun1James Kryzanski2Michael Lanfranchi3Gaurav K. Gupta4Harprit Bedi5Department of Radiology, Tufts Medical Center, Boston, MA, USADepartment of Pathology and Laboratory Medicine, Tufts Medical Center, Boston, MA, USADepartment of Neurosurgery, Tufts Medical Center, Boston, MA, USADepartment of Radiology, Massachusetts General Hospital, Boston, MA, USADepartment of Pathology and Laboratory Medicine, Tufts Medical Center, Boston, MA, USADepartment of Radiology, Tufts Medical Center, Boston, MA, USAEpendymomas are common spinal lesions, with the vast majority arising in an intramedullary location. Several cases have been described in the literature of ependymomas in an intradural, extramedullary location. The authors present a case of a 56-year-old female who presented with several weeks of lower back pain and weakness. MRI revealed an intradural, extramedullary enhancing mass at L1-L2. The mass was successfully resected surgically. Pathologic evaluation revealed a low grade glioma with components of both ependymoma and pilocytic astrocytoma with MUTYH G382D mutation. Extramedullary ependymomas are very rare tumors. To the authors’ knowledge, this is the first case of ependymoma/astrocytoma collision tumors described in an extramedullary location.http://dx.doi.org/10.1155/2016/3534791 |
| spellingShingle | Gene M. Weinstein Knarik Arkun James Kryzanski Michael Lanfranchi Gaurav K. Gupta Harprit Bedi Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the Literature Case Reports in Pathology |
| title | Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the Literature |
| title_full | Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the Literature |
| title_fullStr | Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the Literature |
| title_full_unstemmed | Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the Literature |
| title_short | Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the Literature |
| title_sort | spinal intradural extramedullary ependymoma with astrocytoma component a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2016/3534791 |
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