T and B cell epitope analysis for the immunogenicity evaluation and mitigation of antibody-based therapeutics
The surge in the clinical use of therapeutic antibodies has reshaped the landscape of pharmaceutical therapy for many diseases, including rare and challenging conditions. However, the administration of exogenous biologics could potentially trigger unwanted immune responses such as generation of anti...
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Main Authors: | Ruoxuan Sun, Mark G. Qian, Xiaobin Zhang |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2024-12-01
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Series: | mAbs |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/19420862.2024.2324836 |
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