Characteristics of Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) Strains Isolated from Skin and Soft-Tissue Infections in Uruguay
We analyzed 90 nonduplicates community-associated methicillin-resistant S. aureus (CA-MRSA) strains isolated from skin and soft-tissue infections. All strains were mecA positive. Twenty-four of the 90 strains showed inducible macrolide-lincosamide-streptogramin B resistance. All strains produced α-t...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | International Journal of Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2009/472126 |
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| author | Lorena Pardo Virginia Machado Marta Mollerach María Inés Mota Lorena P. N. Tuchscherr Pilar Gadea Noella Gardella Daniel O. Sordelli Magdalena Vola Felipe Schelotto Gustavo Varela |
| author_facet | Lorena Pardo Virginia Machado Marta Mollerach María Inés Mota Lorena P. N. Tuchscherr Pilar Gadea Noella Gardella Daniel O. Sordelli Magdalena Vola Felipe Schelotto Gustavo Varela |
| author_sort | Lorena Pardo |
| collection | DOAJ |
| description | We analyzed 90 nonduplicates community-associated methicillin-resistant S. aureus (CA-MRSA) strains isolated from skin and soft-tissue infections. All strains were mecA positive. Twenty-four of the 90 strains showed inducible macrolide-lincosamide-streptogramin B resistance. All strains produced α-toxin; 96% and 100% of them displayed positive results for lukS-F and cna genes, respectively. Eigthy-five strains expressed capsular polysaccharide serotype 8. Six different pulsotypes were discriminated by pulsed-field gel electrophoresis (PFGE) and three predominant groups of CA-MRSA strains (1, 2, and 4) were identified, in agreement with phenotypic and genotypic characteristics. Strains of group 1
(pulsotype A, CP8+, and Panton-Valentine leukocidin (PVL)+) were the most frequently recovered and exhibited a PFGE band pattern identical to other CA-MRSA strains previously isolated in Uruguay and Brazil.
Three years after the first local CA-MRSA report, these strains are still producing skin and soft-tissue infections demonstrating the stability over time of this community-associated emerging pathogen. |
| format | Article |
| id | doaj-art-356de3fd19fa47d68f67b9d04e837638 |
| institution | Kabale University |
| issn | 1687-918X 1687-9198 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Microbiology |
| spelling | doaj-art-356de3fd19fa47d68f67b9d04e8376382025-08-20T03:55:16ZengWileyInternational Journal of Microbiology1687-918X1687-91982009-01-01200910.1155/2009/472126472126Characteristics of Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) Strains Isolated from Skin and Soft-Tissue Infections in UruguayLorena Pardo0Virginia Machado1Marta Mollerach2María Inés Mota3Lorena P. N. Tuchscherr4Pilar Gadea5Noella Gardella6Daniel O. Sordelli7Magdalena Vola8Felipe Schelotto9Gustavo Varela10Department of Bacteriology and Virology, Institute of Hygiene, School of Medicine, Universidad de la República, Alfredo Navarro, 3051 Montevideo, UruguayDepartment of Bacteriology and Virology, Institute of Hygiene, School of Medicine, Universidad de la República, Alfredo Navarro, 3051 Montevideo, UruguayCátedra de Microbiología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, 1113 Buenos Aires, ArgentinaDepartment of Bacteriology and Virology, Institute of Hygiene, School of Medicine, Universidad de la República, Alfredo Navarro, 3051 Montevideo, UruguayDepartment of Microbiology, School of Medicine, University of Buenos Aires, 1113 Buenos Aires, ArgentinaDepartment of Bacteriology and Virology, Institute of Hygiene, School of Medicine, Universidad de la República, Alfredo Navarro, 3051 Montevideo, UruguayCátedra de Microbiología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, 1113 Buenos Aires, ArgentinaDepartment of Microbiology, School of Medicine, University of Buenos Aires, 1113 Buenos Aires, ArgentinaDepartment of Bacteriology and Virology, Institute of Hygiene, School of Medicine, Universidad de la República, Alfredo Navarro, 3051 Montevideo, UruguayDepartment of Bacteriology and Virology, Institute of Hygiene, School of Medicine, Universidad de la República, Alfredo Navarro, 3051 Montevideo, UruguayDepartment of Bacteriology and Virology, Institute of Hygiene, School of Medicine, Universidad de la República, Alfredo Navarro, 3051 Montevideo, UruguayWe analyzed 90 nonduplicates community-associated methicillin-resistant S. aureus (CA-MRSA) strains isolated from skin and soft-tissue infections. All strains were mecA positive. Twenty-four of the 90 strains showed inducible macrolide-lincosamide-streptogramin B resistance. All strains produced α-toxin; 96% and 100% of them displayed positive results for lukS-F and cna genes, respectively. Eigthy-five strains expressed capsular polysaccharide serotype 8. Six different pulsotypes were discriminated by pulsed-field gel electrophoresis (PFGE) and three predominant groups of CA-MRSA strains (1, 2, and 4) were identified, in agreement with phenotypic and genotypic characteristics. Strains of group 1 (pulsotype A, CP8+, and Panton-Valentine leukocidin (PVL)+) were the most frequently recovered and exhibited a PFGE band pattern identical to other CA-MRSA strains previously isolated in Uruguay and Brazil. Three years after the first local CA-MRSA report, these strains are still producing skin and soft-tissue infections demonstrating the stability over time of this community-associated emerging pathogen.http://dx.doi.org/10.1155/2009/472126 |
| spellingShingle | Lorena Pardo Virginia Machado Marta Mollerach María Inés Mota Lorena P. N. Tuchscherr Pilar Gadea Noella Gardella Daniel O. Sordelli Magdalena Vola Felipe Schelotto Gustavo Varela Characteristics of Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) Strains Isolated from Skin and Soft-Tissue Infections in Uruguay International Journal of Microbiology |
| title | Characteristics of Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) Strains Isolated from Skin and Soft-Tissue Infections in Uruguay |
| title_full | Characteristics of Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) Strains Isolated from Skin and Soft-Tissue Infections in Uruguay |
| title_fullStr | Characteristics of Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) Strains Isolated from Skin and Soft-Tissue Infections in Uruguay |
| title_full_unstemmed | Characteristics of Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) Strains Isolated from Skin and Soft-Tissue Infections in Uruguay |
| title_short | Characteristics of Community-Associated Methicillin-Resistant Staphylococcus aureus (CA-MRSA) Strains Isolated from Skin and Soft-Tissue Infections in Uruguay |
| title_sort | characteristics of community associated methicillin resistant staphylococcus aureus ca mrsa strains isolated from skin and soft tissue infections in uruguay |
| url | http://dx.doi.org/10.1155/2009/472126 |
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