Effectiveness of a nurse-led pain management model following TACE: a retrospective analysis

Abstract This study aimed to evaluate the clinical effectiveness of a nurse-led pain management model in patients undergoing transarterial chemoembolization (TACE) for primary liver cancer. The model included four key components: (1) dynamic pain assessment using the Numerical Rating Scale (NRS); (2...

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Main Authors: Yili Qu, Haizhi Xu, Xianjun Guo, Chunyan Zhang, Bei Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-09399-9
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author Yili Qu
Haizhi Xu
Xianjun Guo
Chunyan Zhang
Bei Xu
author_facet Yili Qu
Haizhi Xu
Xianjun Guo
Chunyan Zhang
Bei Xu
author_sort Yili Qu
collection DOAJ
description Abstract This study aimed to evaluate the clinical effectiveness of a nurse-led pain management model in patients undergoing transarterial chemoembolization (TACE) for primary liver cancer. The model included four key components: (1) dynamic pain assessment using the Numerical Rating Scale (NRS); (2) individualized non-pharmacological comfort interventions; (3) early mobilization support; and (4) patient education and post-discharge follow-up. The objective was to determine whether this structured nursing model could improve postoperative outcomes compared to conventional care. This retrospective study included 90 patients who underwent c-TACE for primary liver cancer at our hospital. Patients were divided into two groups: the control group (n = 45, May–July 2023) received standard care, while the experimental group (n = 45, August–October 2023) received the nurse-led pain management model in addition to standard care. NRS scores were recorded at 24 and 72 h postoperatively, and comfort, satisfaction, and complication rates were assessed on the day of discharge. Baseline characteristics were comparable between the two groups. At 24 h post-TACE, NRS scores showed no significant difference between the experimental (4.58 ± 1.12) and control (4.69 ± 1.05) groups (P = 0.648). However, by 72 h, the experimental group had significantly lower NRS scores (2.58 ± 0.79 vs. 3.62 ± 0.91, P < 0.001). Comfort and satisfaction scores were significantly higher in the experimental group (P < 0.01), while the overall complication rate was lower (P < 0.05). The nurse-led structured pain management model significantly improved pain control, patient comfort, and satisfaction while reducing postoperative complications. This scalable approach may serve as an effective adjunct to conventional postoperative care following TACE.
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spelling doaj-art-356d02e99fa14178a6749ba223ba0d292025-08-20T03:43:11ZengNature PortfolioScientific Reports2045-23222025-07-0115111010.1038/s41598-025-09399-9Effectiveness of a nurse-led pain management model following TACE: a retrospective analysisYili Qu0Haizhi Xu1Xianjun Guo2Chunyan Zhang3Bei Xu4General Surgery, The Third Affiliated Hospital of Naval Medical UniversityDepartment of Radiotherapy and Hematology, The Third Affiliated Hospital of Naval Medical UniversityDepartment of Emergency Medicine, Armed Police Corps Hospital of ShanghaiGeneral Surgery, The Third Affiliated Hospital of Naval Medical UniversityGeneral Surgery, The Third Affiliated Hospital of Naval Medical UniversityAbstract This study aimed to evaluate the clinical effectiveness of a nurse-led pain management model in patients undergoing transarterial chemoembolization (TACE) for primary liver cancer. The model included four key components: (1) dynamic pain assessment using the Numerical Rating Scale (NRS); (2) individualized non-pharmacological comfort interventions; (3) early mobilization support; and (4) patient education and post-discharge follow-up. The objective was to determine whether this structured nursing model could improve postoperative outcomes compared to conventional care. This retrospective study included 90 patients who underwent c-TACE for primary liver cancer at our hospital. Patients were divided into two groups: the control group (n = 45, May–July 2023) received standard care, while the experimental group (n = 45, August–October 2023) received the nurse-led pain management model in addition to standard care. NRS scores were recorded at 24 and 72 h postoperatively, and comfort, satisfaction, and complication rates were assessed on the day of discharge. Baseline characteristics were comparable between the two groups. At 24 h post-TACE, NRS scores showed no significant difference between the experimental (4.58 ± 1.12) and control (4.69 ± 1.05) groups (P = 0.648). However, by 72 h, the experimental group had significantly lower NRS scores (2.58 ± 0.79 vs. 3.62 ± 0.91, P < 0.001). Comfort and satisfaction scores were significantly higher in the experimental group (P < 0.01), while the overall complication rate was lower (P < 0.05). The nurse-led structured pain management model significantly improved pain control, patient comfort, and satisfaction while reducing postoperative complications. This scalable approach may serve as an effective adjunct to conventional postoperative care following TACE.https://doi.org/10.1038/s41598-025-09399-9Primary liver cancerTransarterial chemoembolizationPostoperative painNurse-led modelDynamic pain assessmentNon-pharmacologic intervention
spellingShingle Yili Qu
Haizhi Xu
Xianjun Guo
Chunyan Zhang
Bei Xu
Effectiveness of a nurse-led pain management model following TACE: a retrospective analysis
Scientific Reports
Primary liver cancer
Transarterial chemoembolization
Postoperative pain
Nurse-led model
Dynamic pain assessment
Non-pharmacologic intervention
title Effectiveness of a nurse-led pain management model following TACE: a retrospective analysis
title_full Effectiveness of a nurse-led pain management model following TACE: a retrospective analysis
title_fullStr Effectiveness of a nurse-led pain management model following TACE: a retrospective analysis
title_full_unstemmed Effectiveness of a nurse-led pain management model following TACE: a retrospective analysis
title_short Effectiveness of a nurse-led pain management model following TACE: a retrospective analysis
title_sort effectiveness of a nurse led pain management model following tace a retrospective analysis
topic Primary liver cancer
Transarterial chemoembolization
Postoperative pain
Nurse-led model
Dynamic pain assessment
Non-pharmacologic intervention
url https://doi.org/10.1038/s41598-025-09399-9
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