THE MECHANISMS OF HEART FAILURE DEVELOPMENT IN OBESITY

The epidemic of obesity impacts significantly the prevalence of cardiovascular diseases, including heart failure. Obesity facilitates proinflammatory status onset, that leads to changes in metabolism of free fatty acids, lipids, glucose, influencing myocardial function and heart failure progression...

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Bibliographic Details
Main Authors: O. V. Gritsenko, G. A. Chumakova, I. V. Shevlyakov, E. V. Trubina
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2018-06-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/2719
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Summary:The epidemic of obesity impacts significantly the prevalence of cardiovascular diseases, including heart failure. Obesity facilitates proinflammatory status onset, that leads to changes in metabolism of free fatty acids, lipids, glucose, influencing myocardial function and heart failure progression from diastolic to systolic. Also, there is data confirming influence of obesity on central and peripheral hemodynamics. To understand these mechanisms is necessary for development of prevention activities against chronic heart failure and other cardiovascular events.
ISSN:1560-4071
2618-7620