Herpesvirus-associated central and peripheral nervous system involvement: two clinical cases

Herpesviruses can directly affect the structure of the nervous system, resulting in encephalitis, and also induce immune-mediated disorders of the peripheral nervous system as sensory-predominant chronic inflammatory demyelinating polyneuropathy (CIDP). Patients with immunodeficiency may simultaneou...

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Main Authors: T. E. Popova, N. A. Shnayder, M. M. Petrova, T. Ya. Nikolaeva, E. A. Kantimirova, N. V. Isaeva, V. A. Shnayder, Yu. S. Panina, A. V. Dyuzhakova, S. K. Dyuzhakov
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2015-06-01
Series:Неврология, нейропсихиатрия, психосоматика
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Online Access:https://nnp.ima-press.net/nnp/article/view/508
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author T. E. Popova
N. A. Shnayder
M. M. Petrova
T. Ya. Nikolaeva
E. A. Kantimirova
N. V. Isaeva
V. A. Shnayder
Yu. S. Panina
A. V. Dyuzhakova
S. K. Dyuzhakov
author_facet T. E. Popova
N. A. Shnayder
M. M. Petrova
T. Ya. Nikolaeva
E. A. Kantimirova
N. V. Isaeva
V. A. Shnayder
Yu. S. Panina
A. V. Dyuzhakova
S. K. Dyuzhakov
author_sort T. E. Popova
collection DOAJ
description Herpesviruses can directly affect the structure of the nervous system, resulting in encephalitis, and also induce immune-mediated disorders of the peripheral nervous system as sensory-predominant chronic inflammatory demyelinating polyneuropathy (CIDP). Patients with immunodeficiency may simultaneously develop two pathological processes, determining the severity of the condition. Parainfectious limbic encephalitis (PILE) associated with viruses from the family Herpes viridae is a form of chronic herpes encephalitis, which is characterized by dysfunction of the limbic system and by a long-term course with exacerbations. CIDP is a dysimmune disease leasing to peripheral nervous system involvement, which belongs to a class of myelinopathies. The paper describes two clinical cases of a concurrence of chronic PILE and CIDP in middle-aged men who have symptomatic status epilepticus and iatrogenic complications. It characterizes difficulties in diagnosis and the clinical features of chronic herpes infection involving the central and peripheral nervous systems. The given clinical cases suggest that not only neurologistsand epileptologists, but also resuscitation specialists and ngiosurgeons should be particularly alert to the pathology in question.
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series Неврология, нейропсихиатрия, психосоматика
spelling doaj-art-355bc6b5ea8847ed87884b0eaecdd9862025-08-20T02:16:14ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422015-06-0172283410.14412/2074-2711-2015-2-28-34480Herpesvirus-associated central and peripheral nervous system involvement: two clinical casesT. E. Popova0N. A. Shnayder1M. M. Petrova2T. Ya. Nikolaeva3E. A. Kantimirova4N. V. Isaeva5V. A. Shnayder6Yu. S. Panina7A. V. Dyuzhakova8S. K. Dyuzhakov9Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia, Krasnoyarsk, Russia 1, Partisan Zheleznyak St., Krasnoyarsk 660022Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia, Krasnoyarsk, Russia 1, Partisan Zheleznyak St., Krasnoyarsk 660022 Clinical Hospital Fifty-One, Federal Biomedical Agency of the Russian Federation, Zheleznogorsk, Russia 5, Kirov St., Zheleznogorsk 662971Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia, Krasnoyarsk, Russia 1, Partisan Zheleznyak St., Krasnoyarsk 660022M.K. Amosov North-Eastern Federal University, Ministry of Education of Russia, Yakutsk, Russia 27, Oiunsky St., Yakutsk 677000Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia, Krasnoyarsk, Russia 1, Partisan Zheleznyak St., Krasnoyarsk 660022Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia, Krasnoyarsk, Russia 1, Partisan Zheleznyak St., Krasnoyarsk 660022 Territorial Clinical Hospital, Krasnoyarsk, Russia 3, Partisan Zheleznyak St., Krasnoyarsk 660022Territorial Clinical Hospital, Krasnoyarsk, Russia 3, Partisan Zheleznyak St., Krasnoyarsk 660022Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia, Krasnoyarsk, Russia 1, Partisan Zheleznyak St., Krasnoyarsk 660022Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia, Krasnoyarsk, Russia 1, Partisan Zheleznyak St., Krasnoyarsk 660022Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia, Krasnoyarsk, Russia 1, Partisan Zheleznyak St., Krasnoyarsk 660022Herpesviruses can directly affect the structure of the nervous system, resulting in encephalitis, and also induce immune-mediated disorders of the peripheral nervous system as sensory-predominant chronic inflammatory demyelinating polyneuropathy (CIDP). Patients with immunodeficiency may simultaneously develop two pathological processes, determining the severity of the condition. Parainfectious limbic encephalitis (PILE) associated with viruses from the family Herpes viridae is a form of chronic herpes encephalitis, which is characterized by dysfunction of the limbic system and by a long-term course with exacerbations. CIDP is a dysimmune disease leasing to peripheral nervous system involvement, which belongs to a class of myelinopathies. The paper describes two clinical cases of a concurrence of chronic PILE and CIDP in middle-aged men who have symptomatic status epilepticus and iatrogenic complications. It characterizes difficulties in diagnosis and the clinical features of chronic herpes infection involving the central and peripheral nervous systems. The given clinical cases suggest that not only neurologistsand epileptologists, but also resuscitation specialists and ngiosurgeons should be particularly alert to the pathology in question.https://nnp.ima-press.net/nnp/article/view/508chronic parainfectious limbic encephalitissensory-predominant chronic inflammatory demyelinating polyneuropathydiagnosisherpesvirusesstatus epilepticuscomplications
spellingShingle T. E. Popova
N. A. Shnayder
M. M. Petrova
T. Ya. Nikolaeva
E. A. Kantimirova
N. V. Isaeva
V. A. Shnayder
Yu. S. Panina
A. V. Dyuzhakova
S. K. Dyuzhakov
Herpesvirus-associated central and peripheral nervous system involvement: two clinical cases
Неврология, нейропсихиатрия, психосоматика
chronic parainfectious limbic encephalitis
sensory-predominant chronic inflammatory demyelinating polyneuropathy
diagnosis
herpesviruses
status epilepticus
complications
title Herpesvirus-associated central and peripheral nervous system involvement: two clinical cases
title_full Herpesvirus-associated central and peripheral nervous system involvement: two clinical cases
title_fullStr Herpesvirus-associated central and peripheral nervous system involvement: two clinical cases
title_full_unstemmed Herpesvirus-associated central and peripheral nervous system involvement: two clinical cases
title_short Herpesvirus-associated central and peripheral nervous system involvement: two clinical cases
title_sort herpesvirus associated central and peripheral nervous system involvement two clinical cases
topic chronic parainfectious limbic encephalitis
sensory-predominant chronic inflammatory demyelinating polyneuropathy
diagnosis
herpesviruses
status epilepticus
complications
url https://nnp.ima-press.net/nnp/article/view/508
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