Obesity Reduces Cognitive and Motor Functions across the Lifespan
Due to a sedentary lifestyle, more and more people are becoming obese nowadays. In addition to health-related problems, obesity can also impair cognition and motor performance. Previous results have shown that obesity mainly affects cognition and motor behaviors through altering brain functions and...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2016/2473081 |
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| _version_ | 1850157516662505472 |
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| author | Chuanming Wang John S. Y. Chan Lijie Ren Jin H. Yan |
| author_facet | Chuanming Wang John S. Y. Chan Lijie Ren Jin H. Yan |
| author_sort | Chuanming Wang |
| collection | DOAJ |
| description | Due to a sedentary lifestyle, more and more people are becoming obese nowadays. In addition to health-related problems, obesity can also impair cognition and motor performance. Previous results have shown that obesity mainly affects cognition and motor behaviors through altering brain functions and musculoskeletal system, respectively. Many factors, such as insulin/leptin dysregulation and inflammation, mediate the effect of obesity and cognition and motor behaviors. Substantial evidence has suggested exercise to be an effective way to improve obesity and related cognitive and motor dysfunctions. This paper aims to discuss the association of obesity with cognition and motor behaviors and its underlying mechanisms. Following this, mechanisms of exercise to improve obesity-related dysfunctions are described. Finally, implications and future research direction are raised. |
| format | Article |
| id | doaj-art-355a38f3fa3f43a4a973d405a0d7670e |
| institution | OA Journals |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-355a38f3fa3f43a4a973d405a0d7670e2025-08-20T02:24:08ZengWileyNeural Plasticity2090-59041687-54432016-01-01201610.1155/2016/24730812473081Obesity Reduces Cognitive and Motor Functions across the LifespanChuanming Wang0John S. Y. Chan1Lijie Ren2Jin H. Yan3Department of Neurology, The Affiliated Shenzhen Nanshan Hospital, Shenzhen University, Shenzhen 518000, ChinaCenter for Brain Disorders and Cognitive Neuroscience, Shenzhen University, Shenzhen 518060, ChinaDepartment of Neurology, Shenzhen Second People’s Hospital, Shenzhen University, Shenzhen 518035, ChinaCenter for Brain Disorders and Cognitive Neuroscience, Shenzhen University, Shenzhen 518060, ChinaDue to a sedentary lifestyle, more and more people are becoming obese nowadays. In addition to health-related problems, obesity can also impair cognition and motor performance. Previous results have shown that obesity mainly affects cognition and motor behaviors through altering brain functions and musculoskeletal system, respectively. Many factors, such as insulin/leptin dysregulation and inflammation, mediate the effect of obesity and cognition and motor behaviors. Substantial evidence has suggested exercise to be an effective way to improve obesity and related cognitive and motor dysfunctions. This paper aims to discuss the association of obesity with cognition and motor behaviors and its underlying mechanisms. Following this, mechanisms of exercise to improve obesity-related dysfunctions are described. Finally, implications and future research direction are raised.http://dx.doi.org/10.1155/2016/2473081 |
| spellingShingle | Chuanming Wang John S. Y. Chan Lijie Ren Jin H. Yan Obesity Reduces Cognitive and Motor Functions across the Lifespan Neural Plasticity |
| title | Obesity Reduces Cognitive and Motor Functions across the Lifespan |
| title_full | Obesity Reduces Cognitive and Motor Functions across the Lifespan |
| title_fullStr | Obesity Reduces Cognitive and Motor Functions across the Lifespan |
| title_full_unstemmed | Obesity Reduces Cognitive and Motor Functions across the Lifespan |
| title_short | Obesity Reduces Cognitive and Motor Functions across the Lifespan |
| title_sort | obesity reduces cognitive and motor functions across the lifespan |
| url | http://dx.doi.org/10.1155/2016/2473081 |
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