Torsion-Driven Plectoneme Formation During Nanopore Translocation of DNA Polymers

Torsion-Driven Plectoneme Formation During Nanopore Translocation of DNA Polymers

The transport of DNA polymers through nanoscale pores is central to many biological processes, from bacterial gene exchange to viral infection. In single-molecule nanopore sensing, the detection of nucleic acid and protein analytes relies on the passage of a long biopolymer through a nanoscale apert...

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Bibliographic Details
Main Authors: Fei Zheng, Antonio Suma, Christopher Maffeo, Kaikai Chen, Mohammed Alawami, Jingjie Sha, Aleksei Aksimentiev, Cristian Micheletti, Ulrich F. Keyser
Format: Article
Language:English
Published: American Physical Society 2025-08-01
Series:Physical Review X
Online Access:http://doi.org/10.1103/spyg-kl86
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