African swine fever virus enhances viral replication by increasing intracellular reduced glutathione levels, which suppresses stress granule formation

African swine fever virus enhances viral replication by increasing intracellular reduced glutathione levels, which suppresses stress granule formation

Abstract African swine fever virus (ASFV) is a DNA virus that has significantly impacted the global swine industry. Currently, there are no effective therapies or vaccines against ASFV. Stress granules (SGs), known for their antiviral properties, are not induced during ASFV infection, even though re...

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Bibliographic Details
Main Authors: Han Gao, Taoming Gu, Xiaopeng Gao, Zebu Song, Jing Liu, Yi Song, Guihong Zhang, Yankuo Sun
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Veterinary Research
Subjects:
African swine fever virus (ASFV)
stress granules (SGs)
reduced glutathione (GSH)
Online Access:https://doi.org/10.1186/s13567-024-01433-4
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