Recruitment of renal functional reserve by intravenous amino acid loading in a sheep model of cardiopulmonary bypass

Recruitment of renal functional reserve by intravenous amino acid loading in a sheep model of cardiopulmonary bypass

Abstract Background Cardiopulmonary bypass (CPB) may decrease the renal functional reserve (RFR). However, the temporal changes in RFR after during the recovery period after CPB remains unknown. We assessed RFR before and then weekly after CPB over four weeks following CPB in non-anaesthetised sheep...

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Main Authors: Taku Furukawa, Alemayehu H. Jufar, Clive N. May, Roger G. Evans, Andrew D. Cochrane, Bruno Marino, Peter R. McCall, Sally G. Hood, Ian E. Birchall, Jaishankar Raman, Pei Chen Connie Ow, Anton Trask-Marino, Lachlan F. Miles, Rinaldo Bellomo, Yugeesh R. Lankadeva
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:Intensive Care Medicine Experimental
Subjects:
Cardiopulmonary bypass
Cardiac surgery
Renal functional reserve
Acute kidney injury
Acute kidney disease
Chronic kidney disease
Online Access:https://doi.org/10.1186/s40635-025-00774-4
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