PRACTICE OF EARLY REDUCED-ANTIGENIC-LOAD BCG-M VACCINATION OF HIV-EXPOSED INFANTS

A practice of an early reduced-antigenic-load BCG-M vaccination of HIV-exposed infants inIrkutskdistrict, a district with the high HIV and tuberculosis (TB) prevalence, had been evaluated. It had been establish that the vaccination within the conventional time frame leads to the development of an an...

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Main Authors: S. N. Shugaeva, A. G. Petrova
Format: Article
Language:Russian
Published: LLC "Diagnostics and Vaccines" 2015-08-01
Series:Детские инфекции (Москва)
Subjects:
Online Access:https://detinf.elpub.ru/jour/article/view/24
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author S. N. Shugaeva
A. G. Petrova
author_facet S. N. Shugaeva
A. G. Petrova
author_sort S. N. Shugaeva
collection DOAJ
description A practice of an early reduced-antigenic-load BCG-M vaccination of HIV-exposed infants inIrkutskdistrict, a district with the high HIV and tuberculosis (TB) prevalence, had been evaluated. It had been establish that the vaccination within the conventional time frame leads to the development of an anti-tuberculous immune response which, usually, is verified by the post-immunization reactions and the tuberculosis skin test results. A high safety of the reduced-antigenic-load BCG-M vaccination had been confirmed in cases with perinatally HIV-infected infants. The clinical development of the TB infection in non-vaccinated children, especially of the youngest age, had been characterized by a development of the hazardous complications which tend to be persistent.
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publisher LLC "Diagnostics and Vaccines"
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spelling doaj-art-3545a8fbd8cf4608ac70ecd24cfa08f02025-08-20T02:46:40ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072015-08-01132343610.22627/2072-8107-2014-13-2-34-3624PRACTICE OF EARLY REDUCED-ANTIGENIC-LOAD BCG-M VACCINATION OF HIV-EXPOSED INFANTSS. N. Shugaeva0A. G. Petrova1Irkutsk State Medical Academy of Postgraduate StudieIrkutsk State Medical UniversityA practice of an early reduced-antigenic-load BCG-M vaccination of HIV-exposed infants inIrkutskdistrict, a district with the high HIV and tuberculosis (TB) prevalence, had been evaluated. It had been establish that the vaccination within the conventional time frame leads to the development of an anti-tuberculous immune response which, usually, is verified by the post-immunization reactions and the tuberculosis skin test results. A high safety of the reduced-antigenic-load BCG-M vaccination had been confirmed in cases with perinatally HIV-infected infants. The clinical development of the TB infection in non-vaccinated children, especially of the youngest age, had been characterized by a development of the hazardous complications which tend to be persistent.https://detinf.elpub.ru/jour/article/view/24bcg-m vaccinationtuberculosishiv-infectioninfants
spellingShingle S. N. Shugaeva
A. G. Petrova
PRACTICE OF EARLY REDUCED-ANTIGENIC-LOAD BCG-M VACCINATION OF HIV-EXPOSED INFANTS
Детские инфекции (Москва)
bcg-m vaccination
tuberculosis
hiv-infection
infants
title PRACTICE OF EARLY REDUCED-ANTIGENIC-LOAD BCG-M VACCINATION OF HIV-EXPOSED INFANTS
title_full PRACTICE OF EARLY REDUCED-ANTIGENIC-LOAD BCG-M VACCINATION OF HIV-EXPOSED INFANTS
title_fullStr PRACTICE OF EARLY REDUCED-ANTIGENIC-LOAD BCG-M VACCINATION OF HIV-EXPOSED INFANTS
title_full_unstemmed PRACTICE OF EARLY REDUCED-ANTIGENIC-LOAD BCG-M VACCINATION OF HIV-EXPOSED INFANTS
title_short PRACTICE OF EARLY REDUCED-ANTIGENIC-LOAD BCG-M VACCINATION OF HIV-EXPOSED INFANTS
title_sort practice of early reduced antigenic load bcg m vaccination of hiv exposed infants
topic bcg-m vaccination
tuberculosis
hiv-infection
infants
url https://detinf.elpub.ru/jour/article/view/24
work_keys_str_mv AT snshugaeva practiceofearlyreducedantigenicloadbcgmvaccinationofhivexposedinfants
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