Exploratory GABAa-informed control network modulates hyperarousal brain dynamics in chronic insomnia

Abstract Chronic insomnia disorder is characterized by hyperarousal, a heightened cortical activation pattern that disrupts normal sleep. While hyperarousal has been linked to altered brain state dynamics, the underlying neurobiological mechanisms remain poorly understood, particularly regarding the...

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Bibliographic Details
Main Authors: Liyong Yu, Liang Gong, Xiaoqin Chen, Yuqi He, Rong Li, Xiaojuan Hong, Qi Zhang, Siyi Yu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08439-4
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