CircSLC22A3 inhibits the invasion and metastasis of ESCC via the miR-19b-3p/TRAK2 axis and by reducing the stability of m6A-modified ACSBG1 mRNA

CircSLC22A3 inhibits the invasion and metastasis of ESCC via the miR-19b-3p/TRAK2 axis and by reducing the stability of m6A-modified ACSBG1 mRNA

Abstract Background Esophageal squamous cell carcinoma (ESCC) is a major contributor to cancer-related deaths, driven by its invasive and metastatic nature. Circular RNAs (circRNAs) are increasingly recognized as regulators of cancer progression, primarily through miRNA sponging and interactions wit...

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Bibliographic Details
Main Authors: Yingjie Pan, Hang Yang, Jiayi Zhang, Ruolan Zhang, Yun Liu, Jun Bie, Qiaoling Chen, Yan Qiao, Kang Liu, Guiqin Song
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cancer
Subjects:
ESCC
circSLC22A3
miR-19b-3p
TRAK2
IGF2BP1
ACSBG1
Online Access:https://doi.org/10.1186/s12885-025-14390-8
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