Direct comparisons of neural activity during placebo analgesia and nocebo hyperalgesia between humans and rats
Abstract Placebo analgesia and nocebo hyperalgesia can profoundly alter pain perception, offering critical implications for pain management. While animal models are increasingly used to explore the underlying mechanisms of these phenomena, it remains unclear whether animals experience placebo and no...
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| Main Authors: | Damien C. Boorman, Lewis S. Crawford, Luke A. Henderson, Kevin A. Keay |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-07993-1 |
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