THE BIOPHARMACEUTICAL INVESTIGATION OF PARACETAMOL SUPPOSITORIES FROM DOMESTIC MANUFACTURERS
The quality of Paracetamol suppositories produced by domestic manufacturers has been investigated and their compliance with pharmacopoeial requirements has been established. Dissolution profile test of paracetamol suppositories of different producers has been carried out and nonequivalence of profil...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
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| Online Access: | https://www.pharmjournal.ru/jour/article/view/85 |
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| _version_ | 1849395880771190784 |
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| author | T. V. Orlova T. A. Pankrusheva N. D. Ogneschikova A. V. Nesterova |
| author_facet | T. V. Orlova T. A. Pankrusheva N. D. Ogneschikova A. V. Nesterova |
| author_sort | T. V. Orlova |
| collection | DOAJ |
| description | The quality of Paracetamol suppositories produced by domestic manufacturers has been investigated and their compliance with pharmacopoeial requirements has been established. Dissolution profile test of paracetamol suppositories of different producers has been carried out and nonequivalence of profiles due to the properties of the suppository basis has been shown. The importance of hydroxyl value and melting point of fat suppository bases used as pharmaceutical factors has been highlighted. |
| format | Article |
| id | doaj-art-352dfe9da92646a28fc2b60cd70dbef2 |
| institution | Kabale University |
| issn | 2305-2066 2658-5049 |
| language | Russian |
| publishDate | 2019-01-01 |
| publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
| record_format | Article |
| series | Разработка и регистрация лекарственных средств |
| spelling | doaj-art-352dfe9da92646a28fc2b60cd70dbef22025-08-20T03:39:29ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0102707585THE BIOPHARMACEUTICAL INVESTIGATION OF PARACETAMOL SUPPOSITORIES FROM DOMESTIC MANUFACTURERST. V. Orlova0T. A. Pankrusheva1N. D. Ogneschikova2A. V. Nesterova3Kursk State Medical UniversityKursk State Medical UniversityKursk State Medical UniversityKursk State Medical UniversityThe quality of Paracetamol suppositories produced by domestic manufacturers has been investigated and their compliance with pharmacopoeial requirements has been established. Dissolution profile test of paracetamol suppositories of different producers has been carried out and nonequivalence of profiles due to the properties of the suppository basis has been shown. The importance of hydroxyl value and melting point of fat suppository bases used as pharmaceutical factors has been highlighted.https://www.pharmjournal.ru/jour/article/view/85paracetamol suppositoriesbiopharmacydissolution profiles |
| spellingShingle | T. V. Orlova T. A. Pankrusheva N. D. Ogneschikova A. V. Nesterova THE BIOPHARMACEUTICAL INVESTIGATION OF PARACETAMOL SUPPOSITORIES FROM DOMESTIC MANUFACTURERS Разработка и регистрация лекарственных средств paracetamol suppositories biopharmacy dissolution profiles |
| title | THE BIOPHARMACEUTICAL INVESTIGATION OF PARACETAMOL SUPPOSITORIES FROM DOMESTIC MANUFACTURERS |
| title_full | THE BIOPHARMACEUTICAL INVESTIGATION OF PARACETAMOL SUPPOSITORIES FROM DOMESTIC MANUFACTURERS |
| title_fullStr | THE BIOPHARMACEUTICAL INVESTIGATION OF PARACETAMOL SUPPOSITORIES FROM DOMESTIC MANUFACTURERS |
| title_full_unstemmed | THE BIOPHARMACEUTICAL INVESTIGATION OF PARACETAMOL SUPPOSITORIES FROM DOMESTIC MANUFACTURERS |
| title_short | THE BIOPHARMACEUTICAL INVESTIGATION OF PARACETAMOL SUPPOSITORIES FROM DOMESTIC MANUFACTURERS |
| title_sort | biopharmaceutical investigation of paracetamol suppositories from domestic manufacturers |
| topic | paracetamol suppositories biopharmacy dissolution profiles |
| url | https://www.pharmjournal.ru/jour/article/view/85 |
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