Embryonal Rhabdomyosarcoma of the Adult Urinary Bladder: A Rare Case Report of Misclassification as Inflammatory Myofibroblastic Tumor

Embryonal rhabdomyosarcoma (ERMS) of the adult urinary bladder is a rare malignant tumour. Inflammatory myofibroblastic tumour (IMT) of the bladder is a benign genitourinary tumour that may appear variable histologically but usually lacks unequivocal malignant traits. Techniques like flow cytometry...

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Main Authors: Kelven Weijing Chen, Fiona Mei Wen Wu, Victor Kwan Min Lee, Kesavan Esuvaranathan
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2015/510508
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author Kelven Weijing Chen
Fiona Mei Wen Wu
Victor Kwan Min Lee
Kesavan Esuvaranathan
author_facet Kelven Weijing Chen
Fiona Mei Wen Wu
Victor Kwan Min Lee
Kesavan Esuvaranathan
author_sort Kelven Weijing Chen
collection DOAJ
description Embryonal rhabdomyosarcoma (ERMS) of the adult urinary bladder is a rare malignant tumour. Inflammatory myofibroblastic tumour (IMT) of the bladder is a benign genitourinary tumour that may appear variable histologically but usually lacks unequivocal malignant traits. Techniques like flow cytometry and immunohistochemistry may be used to differentiate these two tumours. Our patient, a 46-year-old male, had rapidly recurring lower urinary tract symptoms after two transurethral resections of the prostate. He subsequently underwent a transvesical prostatectomy which showed IMT on histology. However, his symptoms did not resolve and an open resection done at our institution revealed a 6 cm tumour arising from the right bladder neck. This time, histology was ERMS with diffuse anaplasia of the bladder. Rapid recurrence of urinary symptoms with prostate regrowth after surgery is unusual. Differential diagnoses of uncommon bladder malignancies should be considered if there is an inconsistent clinical course as treatment approaches are different.
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spelling doaj-art-352cc369ed68491eb7a52885bc7e2fcd2025-08-20T03:55:16ZengWileyCase Reports in Surgery2090-69002090-69192015-01-01201510.1155/2015/510508510508Embryonal Rhabdomyosarcoma of the Adult Urinary Bladder: A Rare Case Report of Misclassification as Inflammatory Myofibroblastic TumorKelven Weijing Chen0Fiona Mei Wen Wu1Victor Kwan Min Lee2Kesavan Esuvaranathan3Department of Urology, National University Health System, 1E Kent Ridge Road, 119228, SingaporeDepartment of Urology, National University Health System, 1E Kent Ridge Road, 119228, SingaporeDepartment of Pathology, National University Health System, 1E Kent Ridge Road, 119228, SingaporeDepartment of Urology, National University Health System, 1E Kent Ridge Road, 119228, SingaporeEmbryonal rhabdomyosarcoma (ERMS) of the adult urinary bladder is a rare malignant tumour. Inflammatory myofibroblastic tumour (IMT) of the bladder is a benign genitourinary tumour that may appear variable histologically but usually lacks unequivocal malignant traits. Techniques like flow cytometry and immunohistochemistry may be used to differentiate these two tumours. Our patient, a 46-year-old male, had rapidly recurring lower urinary tract symptoms after two transurethral resections of the prostate. He subsequently underwent a transvesical prostatectomy which showed IMT on histology. However, his symptoms did not resolve and an open resection done at our institution revealed a 6 cm tumour arising from the right bladder neck. This time, histology was ERMS with diffuse anaplasia of the bladder. Rapid recurrence of urinary symptoms with prostate regrowth after surgery is unusual. Differential diagnoses of uncommon bladder malignancies should be considered if there is an inconsistent clinical course as treatment approaches are different.http://dx.doi.org/10.1155/2015/510508
spellingShingle Kelven Weijing Chen
Fiona Mei Wen Wu
Victor Kwan Min Lee
Kesavan Esuvaranathan
Embryonal Rhabdomyosarcoma of the Adult Urinary Bladder: A Rare Case Report of Misclassification as Inflammatory Myofibroblastic Tumor
Case Reports in Surgery
title Embryonal Rhabdomyosarcoma of the Adult Urinary Bladder: A Rare Case Report of Misclassification as Inflammatory Myofibroblastic Tumor
title_full Embryonal Rhabdomyosarcoma of the Adult Urinary Bladder: A Rare Case Report of Misclassification as Inflammatory Myofibroblastic Tumor
title_fullStr Embryonal Rhabdomyosarcoma of the Adult Urinary Bladder: A Rare Case Report of Misclassification as Inflammatory Myofibroblastic Tumor
title_full_unstemmed Embryonal Rhabdomyosarcoma of the Adult Urinary Bladder: A Rare Case Report of Misclassification as Inflammatory Myofibroblastic Tumor
title_short Embryonal Rhabdomyosarcoma of the Adult Urinary Bladder: A Rare Case Report of Misclassification as Inflammatory Myofibroblastic Tumor
title_sort embryonal rhabdomyosarcoma of the adult urinary bladder a rare case report of misclassification as inflammatory myofibroblastic tumor
url http://dx.doi.org/10.1155/2015/510508
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