Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study
Introduction. The kidney affects the thyroid gland causing various derangements in its function whenever the kidney is impaired, even with a minor imperfection in its job, and this makes dialysis patients more prone to thyroid disorders with subsequent increase in mortality and morbidity. This study...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | International Journal of Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2020/2683123 |
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| author | Zaher A. Nazzal Emad N. Khazneh Razan A. Rabi Ahlam A. Hammoudeh Ahmed F. Ghanem Mohammed A. Zaidan |
| author_facet | Zaher A. Nazzal Emad N. Khazneh Razan A. Rabi Ahlam A. Hammoudeh Ahmed F. Ghanem Mohammed A. Zaidan |
| author_sort | Zaher A. Nazzal |
| collection | DOAJ |
| description | Introduction. The kidney affects the thyroid gland causing various derangements in its function whenever the kidney is impaired, even with a minor imperfection in its job, and this makes dialysis patients more prone to thyroid disorders with subsequent increase in mortality and morbidity. This study aims to assess the prevalence of thyroid disease (hypo- and hyperthyroidism) among dialysis patients and their associated factors. Methods. This cross-sectional study was conducted in the dialysis unit of An-Najah National University Hospital. 209 dialysis patients (60% were male, 57.6 ± 14.5 years, mean age) meeting our inclusion criteria were tested for thyrotropin (TSH) and free thyroxine (FT4) in addition to routine laboratory tests. Findings. The prevalence of hypothyroidism was assessed as 16.3% (95% CI = 11.29% to 21.3%), overt hypothyroidism was 9.1%, and subclinical hypothyroidism was 7.2%. Subclinical hyperthyroidism prevalence was 1%, and no overt hyperthyroidism cases were reported. We observed no significant association between thyroid state and age, gender, duration of dialysis, or weight. Discussion. Hypothyroidism (both subclinical and overt type) is commonly seen in dialysis patients, and its symptoms are ordinary complains even in euthyroid dialysis patients, and this warrants screening programs and more studies on the efficacy of thyroid hormone supplements. |
| format | Article |
| id | doaj-art-352c186c9e3042dfac6e2169d8bad4b4 |
| institution | Kabale University |
| issn | 2090-214X 2090-2158 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Nephrology |
| spelling | doaj-art-352c186c9e3042dfac6e2169d8bad4b42025-08-20T03:55:16ZengWileyInternational Journal of Nephrology2090-214X2090-21582020-01-01202010.1155/2020/26831232683123Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional StudyZaher A. Nazzal0Emad N. Khazneh1Razan A. Rabi2Ahlam A. Hammoudeh3Ahmed F. Ghanem4Mohammed A. Zaidan5Department of Family and Community Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, State of PalestineDepartment of Nephrology, An-Najah National University Hospital, Nablus, State of PalestineDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, State of PalestineDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, State of PalestineDepartment of Radiology, An-Najah National University Hospital, Nablus, State of PalestineDepartment of Endocrinology, Istishari Arab Hospital, Ramallah, State of PalestineIntroduction. The kidney affects the thyroid gland causing various derangements in its function whenever the kidney is impaired, even with a minor imperfection in its job, and this makes dialysis patients more prone to thyroid disorders with subsequent increase in mortality and morbidity. This study aims to assess the prevalence of thyroid disease (hypo- and hyperthyroidism) among dialysis patients and their associated factors. Methods. This cross-sectional study was conducted in the dialysis unit of An-Najah National University Hospital. 209 dialysis patients (60% were male, 57.6 ± 14.5 years, mean age) meeting our inclusion criteria were tested for thyrotropin (TSH) and free thyroxine (FT4) in addition to routine laboratory tests. Findings. The prevalence of hypothyroidism was assessed as 16.3% (95% CI = 11.29% to 21.3%), overt hypothyroidism was 9.1%, and subclinical hypothyroidism was 7.2%. Subclinical hyperthyroidism prevalence was 1%, and no overt hyperthyroidism cases were reported. We observed no significant association between thyroid state and age, gender, duration of dialysis, or weight. Discussion. Hypothyroidism (both subclinical and overt type) is commonly seen in dialysis patients, and its symptoms are ordinary complains even in euthyroid dialysis patients, and this warrants screening programs and more studies on the efficacy of thyroid hormone supplements.http://dx.doi.org/10.1155/2020/2683123 |
| spellingShingle | Zaher A. Nazzal Emad N. Khazneh Razan A. Rabi Ahlam A. Hammoudeh Ahmed F. Ghanem Mohammed A. Zaidan Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study International Journal of Nephrology |
| title | Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study |
| title_full | Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study |
| title_fullStr | Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study |
| title_full_unstemmed | Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study |
| title_short | Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study |
| title_sort | prevalence of hypothyroidism among dialysis patients in palestine a cross sectional study |
| url | http://dx.doi.org/10.1155/2020/2683123 |
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