Salivary Duct Carcinoma: Case Reports and Brief Review of the Literature
Salivary duct carcinoma (SDC) is an uncommon and highly aggressive tumor associated with high morbidity and mortality. According to the World Health Organization, it is an extremely rare malignancy with an estimated incidence of 1-1.2 in 1,000,000 patients. Standard treatment for SDC is wide surgica...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/2672772 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850157503985221632 |
|---|---|
| author | Deepti Kantamani Sai S. Bandaru Jennifer L. Miatech M. Patrick Stagg |
| author_facet | Deepti Kantamani Sai S. Bandaru Jennifer L. Miatech M. Patrick Stagg |
| author_sort | Deepti Kantamani |
| collection | DOAJ |
| description | Salivary duct carcinoma (SDC) is an uncommon and highly aggressive tumor associated with high morbidity and mortality. According to the World Health Organization, it is an extremely rare malignancy with an estimated incidence of 1-1.2 in 1,000,000 patients. Standard treatment for SDC is wide surgical resection along with lymph node dissection followed by adjuvant radiation therapy. The role of adjuvant chemotherapy is not known. In this report, we present three cases of SDC. A 71-year-old female with T1N0M0 disease was treated with total parotidectomy, ipsilateral neck dissection, and adjuvant radiotherapy without evidence of disease recurrence at 5 months. The second is a 59-year-old female with TXN1M0 disease who was treated with total parotidectomy with ipsilateral level I-IV neck dissection and adjuvant radiotherapy without evidence of disease occurrence at 21 months. The third case is a 79-year-old male with widely metastatic disease, including brain metastases, treated with cranial irradiation, leuprolide, and lapatinib who remains under home hospice care. |
| format | Article |
| id | doaj-art-352ade2faa36418d9121697a2bd2b6a5 |
| institution | OA Journals |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-352ade2faa36418d9121697a2bd2b6a52025-08-20T02:24:08ZengWileyCase Reports in Oncological Medicine2090-67062090-67142021-01-01202110.1155/2021/26727722672772Salivary Duct Carcinoma: Case Reports and Brief Review of the LiteratureDeepti Kantamani0Sai S. Bandaru1Jennifer L. Miatech2M. Patrick Stagg3Baton Rouge General Medical Center-Bluebonnet, Internal Medicine Residency Program, Baton Rouge, LA, 70809-3679, USABaton Rouge General Medical Center-Bluebonnet, Internal Medicine Residency Program, Baton Rouge, LA, 70809-3679, USABaton Rouge General Medical Center-Bluebonnet, Internal Medicine Residency Program, Baton Rouge, LA, 70809-3679, USABaton Rouge General Medical Center-Bluebonnet, Internal Medicine Residency Program, Baton Rouge, LA, 70809-3679, USASalivary duct carcinoma (SDC) is an uncommon and highly aggressive tumor associated with high morbidity and mortality. According to the World Health Organization, it is an extremely rare malignancy with an estimated incidence of 1-1.2 in 1,000,000 patients. Standard treatment for SDC is wide surgical resection along with lymph node dissection followed by adjuvant radiation therapy. The role of adjuvant chemotherapy is not known. In this report, we present three cases of SDC. A 71-year-old female with T1N0M0 disease was treated with total parotidectomy, ipsilateral neck dissection, and adjuvant radiotherapy without evidence of disease recurrence at 5 months. The second is a 59-year-old female with TXN1M0 disease who was treated with total parotidectomy with ipsilateral level I-IV neck dissection and adjuvant radiotherapy without evidence of disease occurrence at 21 months. The third case is a 79-year-old male with widely metastatic disease, including brain metastases, treated with cranial irradiation, leuprolide, and lapatinib who remains under home hospice care.http://dx.doi.org/10.1155/2021/2672772 |
| spellingShingle | Deepti Kantamani Sai S. Bandaru Jennifer L. Miatech M. Patrick Stagg Salivary Duct Carcinoma: Case Reports and Brief Review of the Literature Case Reports in Oncological Medicine |
| title | Salivary Duct Carcinoma: Case Reports and Brief Review of the Literature |
| title_full | Salivary Duct Carcinoma: Case Reports and Brief Review of the Literature |
| title_fullStr | Salivary Duct Carcinoma: Case Reports and Brief Review of the Literature |
| title_full_unstemmed | Salivary Duct Carcinoma: Case Reports and Brief Review of the Literature |
| title_short | Salivary Duct Carcinoma: Case Reports and Brief Review of the Literature |
| title_sort | salivary duct carcinoma case reports and brief review of the literature |
| url | http://dx.doi.org/10.1155/2021/2672772 |
| work_keys_str_mv | AT deeptikantamani salivaryductcarcinomacasereportsandbriefreviewoftheliterature AT saisbandaru salivaryductcarcinomacasereportsandbriefreviewoftheliterature AT jenniferlmiatech salivaryductcarcinomacasereportsandbriefreviewoftheliterature AT mpatrickstagg salivaryductcarcinomacasereportsandbriefreviewoftheliterature |