The Phytochemistry and Pharmacology of Onocleaceae Plants: <i>Pentarhizidium orientale</i>, <i>Pentarhizidium intermedium</i>, and <i>Matteuccia struthiopteris</i>—A Review

The Onocleaceae family, a small group within the Pteridophytes, comprises four genera, but has been phytochemically studied mainly for <i>Pentarhizidium orientale</i>, <i>Pentarhizidium intermedium</i>, and <i>Matteuccia struthiopteris</i>. To date, a total of 91...

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Bibliographic Details
Main Author: Jungmoo Huh
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Plants
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Online Access:https://www.mdpi.com/2223-7747/14/11/1608
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Summary:The Onocleaceae family, a small group within the Pteridophytes, comprises four genera, but has been phytochemically studied mainly for <i>Pentarhizidium orientale</i>, <i>Pentarhizidium intermedium</i>, and <i>Matteuccia struthiopteris</i>. To date, a total of 91 compounds have been isolated from these three species, including 15 flavonoids, 48 flavonoid glycosides, 6 stilbenes, 4 isocoumarins, 2 phthalides, 3 chromones, 2 lignan glycosides, 8 isoprenoid derivatives, and 3 phenolic compounds. Notably, most flavonoids and flavonoid glycosides possess <i>C</i>-methyl groups at the C-6 and/or C-8 positions, with several conjugated to (<i>S</i>)-3-hydroxy-3-methylglutaryl (HMG) moieties. Although not all isolates have been evaluated for their pharmacological activities, several compounds have demonstrated bioactivities such as antiviral, anti-inflammatory, α-glucosidase inhibitory, aldose reductase inhibitory, and antioxidant effects.
ISSN:2223-7747