Multiple low-dose radiation ameliorates type-2 diabetes mellitus via gut microbiota modulation to activate TLR4/MyD88/NF-κB pathway

Multiple low-dose radiation ameliorates type-2 diabetes mellitus via gut microbiota modulation to activate TLR4/MyD88/NF-κB pathway

Abstract Background Type 2 diabetes mellitus (T2DM) is the fastest-growing metabolic disease in the world. The gut microbiota is linked to T2DM. Recent studies have showed that the metabolism of gut microbiota can trigger T2DM. Low dose radiation (LDR) has been proved to activate various protective...

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Bibliographic Details
Main Authors: Lijing Qin, Rongrong Liu, Zhen Jia, Weiqiang Xu, Li Wang, Hongyuan Tian, Xinru Lian, Wen Li, Yali Qi, Huan He, Zhicheng Wang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Endocrine Disorders
Subjects:
Type 2 diabetes mellitus
Low dose radiation
Gut microbiota
Metabolites
Toll-like receptor 4
Online Access:https://doi.org/10.1186/s12902-025-01861-z
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