Generalized functional varying-index coefficient model for dynamic synergistic gene-environment interactions with binary longitudinal traits.
The genetic basis of complex traits involves the function of many genes with small effects as well as complex gene-gene and gene-environment interactions. As one of the major players in complex diseases, the role of gene-environment interactions has been increasingly recognized. Motivated by epidemi...
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Main Authors: | Jingyi Zhang, Honglang Wang, Yuehua Cui |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2025-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0318103 |
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