Chemotherapeutic efficacy of curcumin against plasma and cardio-hepatorenal electrolyte disruption in dichlorvos-challenged rats via augmentation of Na⁺/K⁺-ATPase and Ca²⁺/Mg²⁺-ATPase activities

Chemotherapeutic efficacy of curcumin against plasma and cardio-hepatorenal electrolyte disruption in dichlorvos-challenged rats via augmentation of Na⁺/K⁺-ATPase and Ca²⁺/Mg²⁺-ATPase activities

Background: Dichlorvos (2,2-dichlorovinyl dimethyl phosphate or DDVP) is an effective organophosphate pesticide extensively employed in various pest management applications. However, it elicits cytotoxicity. Curcumin is a well-known antioxidant phytochemical, but publications lack data on its influe...

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Main Authors: Adio J. Akamo, Boluwatife A. Olagunju, Iyabode A. Kehinde, Naomi M. Akamo, Adetutu O. Ojelabi, Ofem E. Eteng, Ibiyemi O. Opowoye, Adedayo A. Adebisi, Taiwo S. Oguntona, Mushafau A. Akinsanya, Tobi S. Adekunbi, Olufemi M. Ajagun-Ogunleye, Opeyemi E. Popoola, Jacob K. Akintunde, Oluseyi A. Akinloye
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Journal of Trace Elements and Minerals
Subjects:
Curcumin
Dichlorvos
Cardio-hepatorenal
Electrolytes
Ion pump
Online Access:http://www.sciencedirect.com/science/article/pii/S2773050625000394
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