CELLULAR IMMUNITY AND CYTOKINE PROFILE IN PRE-FARROW AND LACTATING SOWS
Study results of cellular immunity and cytokine profile of commercial pre-farrow and lactating sows are shown. Before farrow, the animals demonstrated physiological immunodeficiency characterized by relative leukopenia and lymphopenia, decreased T-cell number, higher helper/suppressor ratio providin...
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| Format: | Article |
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Da Vinci Media
2019-10-01
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| Series: | Ветеринария сегодня |
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| Online Access: | https://veterinary.arriah.ru/jour/article/view/423 |
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| author | A. G. Shakhov S. V. Shabunin L. Yu. Sashnina M. I. Adodina M. Yu. Zhejnes K. V. Tarakanova K. O. Kopytina |
| author_facet | A. G. Shakhov S. V. Shabunin L. Yu. Sashnina M. I. Adodina M. Yu. Zhejnes K. V. Tarakanova K. O. Kopytina |
| author_sort | A. G. Shakhov |
| collection | DOAJ |
| description | Study results of cellular immunity and cytokine profile of commercial pre-farrow and lactating sows are shown. Before farrow, the animals demonstrated physiological immunodeficiency characterized by relative leukopenia and lymphopenia, decreased T-cell number, higher helper/suppressor ratio providing immunological tolerance in dam/fetus system. Their cytokine profile was specified by relatively deficient interleukin-1β and tumor necrosis factor-α indicative of immune system suppression and high level of γ-interferon involved in parturition and activation of suppressor cells. Post-farrow sows demonstrated higher cellular immunity involving higher levels of leukocytes, lymphocytes and T-cells as well as tendency of T-lymphocyte helper/suppressor ratio reduction being indicative of T-cells’ suppressor activity. The cytokine profile of the sows was specified by the recovered numbers of interleukin-1β, tumor necrosis factor-α and γ-interferon, decreased level of interleukin-2 and interleukin-4 that regulate cellular and humoral immunity, respectively as well as their subsequent increase (in particular, interleukin-2) following animal immunization against parvoviral infection and erysipelas on day 7 post farrowing (Parvoruvax vaccine, Merial, France) and against classical swine fever on day 14 post farrowing (culture dry virus-vaccine LK-VNIVIPFIT). This is due to the formation of the cellular and humoral immunity. |
| format | Article |
| id | doaj-art-34fd25e67eb44c40b60401339daab191 |
| institution | Kabale University |
| issn | 2304-196X 2658-6959 |
| language | English |
| publishDate | 2019-10-01 |
| publisher | Da Vinci Media |
| record_format | Article |
| series | Ветеринария сегодня |
| spelling | doaj-art-34fd25e67eb44c40b60401339daab1912025-02-06T09:52:07ZengDa Vinci MediaВетеринария сегодня2304-196X2658-69592019-10-0103152210.29326/2304-196X-2019-3-30-15-18416CELLULAR IMMUNITY AND CYTOKINE PROFILE IN PRE-FARROW AND LACTATING SOWSA. G. Shakhov0S. V. Shabunin1L. Yu. Sashnina2M. I. Adodina3M. Yu. Zhejnes4K. V. Tarakanova5K. O. Kopytina6FGBRI “VNIVIPAT”FGBRI “VNIVIPAT”FGBRI “VNIVIPAT”FGBRI “VNIVIPAT”FGBRI “VNIVIPAT”FGBRI “VNIVIPAT”FGBRI “VNIVIPAT”Study results of cellular immunity and cytokine profile of commercial pre-farrow and lactating sows are shown. Before farrow, the animals demonstrated physiological immunodeficiency characterized by relative leukopenia and lymphopenia, decreased T-cell number, higher helper/suppressor ratio providing immunological tolerance in dam/fetus system. Their cytokine profile was specified by relatively deficient interleukin-1β and tumor necrosis factor-α indicative of immune system suppression and high level of γ-interferon involved in parturition and activation of suppressor cells. Post-farrow sows demonstrated higher cellular immunity involving higher levels of leukocytes, lymphocytes and T-cells as well as tendency of T-lymphocyte helper/suppressor ratio reduction being indicative of T-cells’ suppressor activity. The cytokine profile of the sows was specified by the recovered numbers of interleukin-1β, tumor necrosis factor-α and γ-interferon, decreased level of interleukin-2 and interleukin-4 that regulate cellular and humoral immunity, respectively as well as their subsequent increase (in particular, interleukin-2) following animal immunization against parvoviral infection and erysipelas on day 7 post farrowing (Parvoruvax vaccine, Merial, France) and against classical swine fever on day 14 post farrowing (culture dry virus-vaccine LK-VNIVIPFIT). This is due to the formation of the cellular and humoral immunity.https://veterinary.arriah.ru/jour/article/view/423sowsleukocyteslymphocytest- and b-cellscytokinesimmunodeficiencycellular and humoral immunity |
| spellingShingle | A. G. Shakhov S. V. Shabunin L. Yu. Sashnina M. I. Adodina M. Yu. Zhejnes K. V. Tarakanova K. O. Kopytina CELLULAR IMMUNITY AND CYTOKINE PROFILE IN PRE-FARROW AND LACTATING SOWS Ветеринария сегодня sows leukocytes lymphocytes t- and b-cells cytokines immunodeficiency cellular and humoral immunity |
| title | CELLULAR IMMUNITY AND CYTOKINE PROFILE IN PRE-FARROW AND LACTATING SOWS |
| title_full | CELLULAR IMMUNITY AND CYTOKINE PROFILE IN PRE-FARROW AND LACTATING SOWS |
| title_fullStr | CELLULAR IMMUNITY AND CYTOKINE PROFILE IN PRE-FARROW AND LACTATING SOWS |
| title_full_unstemmed | CELLULAR IMMUNITY AND CYTOKINE PROFILE IN PRE-FARROW AND LACTATING SOWS |
| title_short | CELLULAR IMMUNITY AND CYTOKINE PROFILE IN PRE-FARROW AND LACTATING SOWS |
| title_sort | cellular immunity and cytokine profile in pre farrow and lactating sows |
| topic | sows leukocytes lymphocytes t- and b-cells cytokines immunodeficiency cellular and humoral immunity |
| url | https://veterinary.arriah.ru/jour/article/view/423 |
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