Follicular Lymphoma Manifesting as an Isolated Colorectal Polyp‐Like Morphology
ABSTRACT Background Primary gastrointestinal (GI) follicular lymphoma (FL) is a rare entity, and colorectal FL presenting as a solitary polyp is particularly uncommon. Case Presentation A 60‐year‐old woman presented with hematochezia. Colonoscopy incidentally identified an 8‐mm polyp in the transver...
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| Format: | Article |
| Language: | English |
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Wiley
2025-05-01
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| Series: | JGH Open |
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| Online Access: | https://doi.org/10.1002/jgh3.70170 |
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| author | Yasuhiko Hamada Yuhei Umeda Hayato Nakagawa |
| author_facet | Yasuhiko Hamada Yuhei Umeda Hayato Nakagawa |
| author_sort | Yasuhiko Hamada |
| collection | DOAJ |
| description | ABSTRACT Background Primary gastrointestinal (GI) follicular lymphoma (FL) is a rare entity, and colorectal FL presenting as a solitary polyp is particularly uncommon. Case Presentation A 60‐year‐old woman presented with hematochezia. Colonoscopy incidentally identified an 8‐mm polyp in the transverse colon, which was subsequently removed via cold snare polypectomy. Histopathological examination confirmed Grade 1 FL, with immunohistochemical analysis revealing positivity for CD10, CD20, and Bcl‐2. Further diagnostic evaluation demonstrated FL involvement in the proximal jejunum, leading to a diagnosis of clinical stage I primary GI‐FL. The patient elected to undergo a watch‐and‐wait approach. Conclusion This case highlights the potential for colorectal‐FL lesions to be misidentified as adenomatous polyps, posing a diagnostic challenge. |
| format | Article |
| id | doaj-art-34fc14e4098c48d9b93fc5c593d6d1e2 |
| institution | DOAJ |
| issn | 2397-9070 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | JGH Open |
| spelling | doaj-art-34fc14e4098c48d9b93fc5c593d6d1e22025-08-20T03:05:21ZengWileyJGH Open2397-90702025-05-0195n/an/a10.1002/jgh3.70170Follicular Lymphoma Manifesting as an Isolated Colorectal Polyp‐Like MorphologyYasuhiko Hamada0Yuhei Umeda1Hayato Nakagawa2Department of Gastroenterology and Hepatology Mie University Hospital Tsu JapanDepartment of Gastroenterology and Hepatology Mie University Hospital Tsu JapanDepartment of Gastroenterology and Hepatology Mie University Hospital Tsu JapanABSTRACT Background Primary gastrointestinal (GI) follicular lymphoma (FL) is a rare entity, and colorectal FL presenting as a solitary polyp is particularly uncommon. Case Presentation A 60‐year‐old woman presented with hematochezia. Colonoscopy incidentally identified an 8‐mm polyp in the transverse colon, which was subsequently removed via cold snare polypectomy. Histopathological examination confirmed Grade 1 FL, with immunohistochemical analysis revealing positivity for CD10, CD20, and Bcl‐2. Further diagnostic evaluation demonstrated FL involvement in the proximal jejunum, leading to a diagnosis of clinical stage I primary GI‐FL. The patient elected to undergo a watch‐and‐wait approach. Conclusion This case highlights the potential for colorectal‐FL lesions to be misidentified as adenomatous polyps, posing a diagnostic challenge.https://doi.org/10.1002/jgh3.70170colonoscopycolorectal polypsfollicular lymphoma |
| spellingShingle | Yasuhiko Hamada Yuhei Umeda Hayato Nakagawa Follicular Lymphoma Manifesting as an Isolated Colorectal Polyp‐Like Morphology JGH Open colonoscopy colorectal polyps follicular lymphoma |
| title | Follicular Lymphoma Manifesting as an Isolated Colorectal Polyp‐Like Morphology |
| title_full | Follicular Lymphoma Manifesting as an Isolated Colorectal Polyp‐Like Morphology |
| title_fullStr | Follicular Lymphoma Manifesting as an Isolated Colorectal Polyp‐Like Morphology |
| title_full_unstemmed | Follicular Lymphoma Manifesting as an Isolated Colorectal Polyp‐Like Morphology |
| title_short | Follicular Lymphoma Manifesting as an Isolated Colorectal Polyp‐Like Morphology |
| title_sort | follicular lymphoma manifesting as an isolated colorectal polyp like morphology |
| topic | colonoscopy colorectal polyps follicular lymphoma |
| url | https://doi.org/10.1002/jgh3.70170 |
| work_keys_str_mv | AT yasuhikohamada follicularlymphomamanifestingasanisolatedcolorectalpolyplikemorphology AT yuheiumeda follicularlymphomamanifestingasanisolatedcolorectalpolyplikemorphology AT hayatonakagawa follicularlymphomamanifestingasanisolatedcolorectalpolyplikemorphology |