Minibioreactor arrays to model microbiome response to alcohol and tryptophan in the context of alcohol-associated liver disease

Minibioreactor arrays to model microbiome response to alcohol and tryptophan in the context of alcohol-associated liver disease

Abstract The intestinal microbiota (IM) plays a role in the severity of alcohol-associated liver disease. Modifying severe alcohol-associated hepatitis (AH) dysbiosis improves liver injury through tryptophan (Trp) metabolites and the aryl hydrocarbon receptor (AhR). However, Trp’s effect on the IM i...

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Main Authors: Wanchao Hu, Sabrine Naimi, Nicolas Trainel, Vanessa Liévin-Le Moal, Gabriel Perlemuter, Benoit Chassaing, Dragos Ciocan, Anne-Marie Cassard
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-024-00602-9
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https://doi.org/10.1038/s41522-024-00602-9

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