Immersive Virtual Reality as Computer-Assisted Cognitive–Motor Dual-Task Training in Patients with Parkinson’s Disease

<i>Background and Objectives</i>: The aim of this study was to determine the effect of immersive virtual reality used as a short-term multifaceted activity with a focus on motor and cognitive function in patients with Parkinson’s Disease. The sub-objective focused on quality of life in t...

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Main Authors: Lucie Honzíková, Marcela Dąbrowská, Irena Skřinařová, Kristýna Mullerová, Renáta Čecháčková, Eva Augste, Jana Trdá, Šárka Baníková, Michal Filip, David Školoudík, Iva Štefková, Vojtěch Štula
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Medicina
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Online Access:https://www.mdpi.com/1648-9144/61/2/248
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author Lucie Honzíková
Marcela Dąbrowská
Irena Skřinařová
Kristýna Mullerová
Renáta Čecháčková
Eva Augste
Jana Trdá
Šárka Baníková
Michal Filip
David Školoudík
Iva Štefková
Vojtěch Štula
author_facet Lucie Honzíková
Marcela Dąbrowská
Irena Skřinařová
Kristýna Mullerová
Renáta Čecháčková
Eva Augste
Jana Trdá
Šárka Baníková
Michal Filip
David Školoudík
Iva Štefková
Vojtěch Štula
author_sort Lucie Honzíková
collection DOAJ
description <i>Background and Objectives</i>: The aim of this study was to determine the effect of immersive virtual reality used as a short-term multifaceted activity with a focus on motor and cognitive function in patients with Parkinson’s Disease. The sub-objective focused on quality of life in the study group of patients. <i>Materials and Methods</i>: Nineteen patients (64.2 ± 12.8 years) were included in this study. Inclusion criteria for this study: adult patients in Hoehn and Yahr’s stage 1–3, cooperative, with stable health status, independent and mobile. IVR therapy was performed twice a week for 20 min for one month. Input and output measurements were taken within 14 days of starting or ending therapy. The 10 Meter Walk test was used to examine and assess both comfortable and fast walking, and the Timed Up and Go (TUG) + s dual task was applied to quickly assess the highest possible level of functional mobility. The Berg Balance Scale test (BBS) was used to assess balance with a 14-item balance scale containing specific movement tasks. The standardized Parkinson’s Disease Questionnaire (PDQ-39) was used to assess quality of life. Data were processed in the PAST program using a nonparametric paired Wilcoxon test. The significance level was set at α = 0.05. The value of the r score was used to evaluate the effect size. <i>Results</i>: A significant reduction in the time in the fast walk 10MWT (<i>p</i> = 0.006; r = 0.63) and TUG (<i>p</i> < 0.001; r = 0.80) parameter were found after therapy. Significant improvement in the BBS score was found after applied therapy (<i>p</i> = 0.016; r = 0.55). In the PDQ-39 questionnaire, significant improvements were found in the study group after therapy in the domains of mobility (<i>p</i> = 0.027; r = 0.51) and emotional well-being (<i>p</i> = 0.011; r = 0.58). <i>Conclusions</i>: The results of this study indicate a positive effect of virtual reality therapy on balance and gait, which is also good in terms of reducing the risk of falls in the study group. Therapy also promoted quality of life in the study group.
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spelling doaj-art-34e8db90e56f4ad097dcfb52099773b92025-08-20T02:04:06ZengMDPI AGMedicina1010-660X1648-91442025-02-0161224810.3390/medicina61020248Immersive Virtual Reality as Computer-Assisted Cognitive–Motor Dual-Task Training in Patients with Parkinson’s DiseaseLucie Honzíková0Marcela Dąbrowská1Irena Skřinařová2Kristýna Mullerová3Renáta Čecháčková4Eva Augste5Jana Trdá6Šárka Baníková7Michal Filip8David Školoudík9Iva Štefková10Vojtěch Štula11Department of Rehabilitation and Sports Medicine, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech RepublicDepartment of Rehabilitation and Sports Medicine, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech RepublicDepartment of Rehabilitation and Sports Medicine, University Hospital of Ostrava, 70852 Ostrava, Czech RepublicDepartment of Rehabilitation and Sports Medicine, University Hospital of Ostrava, 70852 Ostrava, Czech RepublicDepartment of Rehabilitation and Sports Medicine, University Hospital of Ostrava, 70852 Ostrava, Czech RepublicInstitute of Physiology and Pathophysiology, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech RepublicVR Vitalis, 70900 Ostrava, Czech RepublicDepartment of Rehabilitation and Sports Medicine, University Hospital of Ostrava, 70852 Ostrava, Czech RepublicDepartment of Rehabilitation and Sports Medicine, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech RepublicDepartment of Clinical Neurosciences, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech RepublicDepartment of Rehabilitation and Sports Medicine, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech RepublicDepartment of Rehabilitation and Sports Medicine, Faculty of Medicine, University of Ostrava, 70300 Ostrava, Czech Republic<i>Background and Objectives</i>: The aim of this study was to determine the effect of immersive virtual reality used as a short-term multifaceted activity with a focus on motor and cognitive function in patients with Parkinson’s Disease. The sub-objective focused on quality of life in the study group of patients. <i>Materials and Methods</i>: Nineteen patients (64.2 ± 12.8 years) were included in this study. Inclusion criteria for this study: adult patients in Hoehn and Yahr’s stage 1–3, cooperative, with stable health status, independent and mobile. IVR therapy was performed twice a week for 20 min for one month. Input and output measurements were taken within 14 days of starting or ending therapy. The 10 Meter Walk test was used to examine and assess both comfortable and fast walking, and the Timed Up and Go (TUG) + s dual task was applied to quickly assess the highest possible level of functional mobility. The Berg Balance Scale test (BBS) was used to assess balance with a 14-item balance scale containing specific movement tasks. The standardized Parkinson’s Disease Questionnaire (PDQ-39) was used to assess quality of life. Data were processed in the PAST program using a nonparametric paired Wilcoxon test. The significance level was set at α = 0.05. The value of the r score was used to evaluate the effect size. <i>Results</i>: A significant reduction in the time in the fast walk 10MWT (<i>p</i> = 0.006; r = 0.63) and TUG (<i>p</i> < 0.001; r = 0.80) parameter were found after therapy. Significant improvement in the BBS score was found after applied therapy (<i>p</i> = 0.016; r = 0.55). In the PDQ-39 questionnaire, significant improvements were found in the study group after therapy in the domains of mobility (<i>p</i> = 0.027; r = 0.51) and emotional well-being (<i>p</i> = 0.011; r = 0.58). <i>Conclusions</i>: The results of this study indicate a positive effect of virtual reality therapy on balance and gait, which is also good in terms of reducing the risk of falls in the study group. Therapy also promoted quality of life in the study group.https://www.mdpi.com/1648-9144/61/2/248balanceclinical trialsmobilityneurodegenerative diseasesquestionnairerehabilitation
spellingShingle Lucie Honzíková
Marcela Dąbrowská
Irena Skřinařová
Kristýna Mullerová
Renáta Čecháčková
Eva Augste
Jana Trdá
Šárka Baníková
Michal Filip
David Školoudík
Iva Štefková
Vojtěch Štula
Immersive Virtual Reality as Computer-Assisted Cognitive–Motor Dual-Task Training in Patients with Parkinson’s Disease
Medicina
balance
clinical trials
mobility
neurodegenerative diseases
questionnaire
rehabilitation
title Immersive Virtual Reality as Computer-Assisted Cognitive–Motor Dual-Task Training in Patients with Parkinson’s Disease
title_full Immersive Virtual Reality as Computer-Assisted Cognitive–Motor Dual-Task Training in Patients with Parkinson’s Disease
title_fullStr Immersive Virtual Reality as Computer-Assisted Cognitive–Motor Dual-Task Training in Patients with Parkinson’s Disease
title_full_unstemmed Immersive Virtual Reality as Computer-Assisted Cognitive–Motor Dual-Task Training in Patients with Parkinson’s Disease
title_short Immersive Virtual Reality as Computer-Assisted Cognitive–Motor Dual-Task Training in Patients with Parkinson’s Disease
title_sort immersive virtual reality as computer assisted cognitive motor dual task training in patients with parkinson s disease
topic balance
clinical trials
mobility
neurodegenerative diseases
questionnaire
rehabilitation
url https://www.mdpi.com/1648-9144/61/2/248
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