Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus
Nurofen Plus is a common analgesic containing ibuprofen and codeine. We present a case of a 38-year-old lady who developed renal tubular acidosis with severe hypokalaemia, after chronic abuse of Nurofen Plus tablets. She presented with confusion and profound biochemical abnormalities requiring criti...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2012/141505 |
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| author | M. J. Blackstock A. Lee |
| author_facet | M. J. Blackstock A. Lee |
| author_sort | M. J. Blackstock |
| collection | DOAJ |
| description | Nurofen Plus is a common analgesic containing ibuprofen and codeine. We present a case of a 38-year-old lady who developed renal tubular acidosis with severe hypokalaemia, after chronic abuse of Nurofen Plus tablets. She presented with confusion and profound biochemical abnormalities requiring critical care admission for electrolyte replacement. Ibuprofen causes renal tubular acidosis due to its effects on carbonic anhydrase activity. |
| format | Article |
| id | doaj-art-34e49820075a42da8e092d0a4345be1a |
| institution | Kabale University |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-34e49820075a42da8e092d0a4345be1a2025-02-03T06:44:31ZengWileyCase Reports in Critical Care2090-64202090-64392012-01-01201210.1155/2012/141505141505Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen PlusM. J. Blackstock0A. Lee1Critical Care, Anaesthesia and Pain Management Department, Royal Infirmary of Edinburgh 51 Little France Crescent, Edinburgh EH16 4SA, UKCritical Care, Anaesthesia and Pain Management Department, Royal Infirmary of Edinburgh 51 Little France Crescent, Edinburgh EH16 4SA, UKNurofen Plus is a common analgesic containing ibuprofen and codeine. We present a case of a 38-year-old lady who developed renal tubular acidosis with severe hypokalaemia, after chronic abuse of Nurofen Plus tablets. She presented with confusion and profound biochemical abnormalities requiring critical care admission for electrolyte replacement. Ibuprofen causes renal tubular acidosis due to its effects on carbonic anhydrase activity.http://dx.doi.org/10.1155/2012/141505 |
| spellingShingle | M. J. Blackstock A. Lee Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus Case Reports in Critical Care |
| title | Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus |
| title_full | Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus |
| title_fullStr | Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus |
| title_full_unstemmed | Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus |
| title_short | Hypokalaemia and Renal Tubular Acidosis due to Abuse of Nurofen Plus |
| title_sort | hypokalaemia and renal tubular acidosis due to abuse of nurofen plus |
| url | http://dx.doi.org/10.1155/2012/141505 |
| work_keys_str_mv | AT mjblackstock hypokalaemiaandrenaltubularacidosisduetoabuseofnurofenplus AT alee hypokalaemiaandrenaltubularacidosisduetoabuseofnurofenplus |