Designing supramolecular pastes by controlling host–guest dynamics in reconfigurable networks

Abstract Stimuli-responsive phase transitions endow smart systems with adaptive functionalities, yet reversible paste-to-gel transitions remain largely unexplored. Here, we report a protonated trianglamine (TA)-based supramolecular paste, in which competitive supramolecular interactions—host–guest b...

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Main Authors: Jinrong Wang, Weibin Lin, Valeriia O. Nikolaeva, Rukhma Javaid, Niveen M. Khashab
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-63033-w
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author Jinrong Wang
Weibin Lin
Valeriia O. Nikolaeva
Rukhma Javaid
Niveen M. Khashab
author_facet Jinrong Wang
Weibin Lin
Valeriia O. Nikolaeva
Rukhma Javaid
Niveen M. Khashab
author_sort Jinrong Wang
collection DOAJ
description Abstract Stimuli-responsive phase transitions endow smart systems with adaptive functionalities, yet reversible paste-to-gel transitions remain largely unexplored. Here, we report a protonated trianglamine (TA)-based supramolecular paste, in which competitive supramolecular interactions—host–guest binding and electrostatic forces—drive the formation of a dynamic TA–clay–polymer ternary network with paste-like rheology. The material exhibits reversible paste-to-gel transitions under mild thermal stimuli, enabling shape reprogramming, temperature-triggered self-healing, and shape fixation. DFT calculations and molecular simulations reveal the molecular basis of the host–guest interactions in guiding network dynamics and healing behavior. Furthermore, incorporating graphene as conductive filler renders the paste functions as a stretchable, self-healing conductive wire, with potential in flexible electronics and responsive devices. This work introduces supramolecular pastes as a versatile class of smart materials that go beyond traditional hydrogels in structural adaptability and multifunctionality.
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institution Kabale University
issn 2041-1723
language English
publishDate 2025-08-01
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spelling doaj-art-34e1d82bcbb248e3847649d178a27b4a2025-08-20T03:42:52ZengNature PortfolioNature Communications2041-17232025-08-0116111510.1038/s41467-025-63033-wDesigning supramolecular pastes by controlling host–guest dynamics in reconfigurable networksJinrong Wang0Weibin Lin1Valeriia O. Nikolaeva2Rukhma Javaid3Niveen M. Khashab4Chemistry Program, Physical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST)Chemistry Program, Physical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST)Chemistry Program, Physical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST)Chemistry Program, Physical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST)Chemistry Program, Physical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST)Abstract Stimuli-responsive phase transitions endow smart systems with adaptive functionalities, yet reversible paste-to-gel transitions remain largely unexplored. Here, we report a protonated trianglamine (TA)-based supramolecular paste, in which competitive supramolecular interactions—host–guest binding and electrostatic forces—drive the formation of a dynamic TA–clay–polymer ternary network with paste-like rheology. The material exhibits reversible paste-to-gel transitions under mild thermal stimuli, enabling shape reprogramming, temperature-triggered self-healing, and shape fixation. DFT calculations and molecular simulations reveal the molecular basis of the host–guest interactions in guiding network dynamics and healing behavior. Furthermore, incorporating graphene as conductive filler renders the paste functions as a stretchable, self-healing conductive wire, with potential in flexible electronics and responsive devices. This work introduces supramolecular pastes as a versatile class of smart materials that go beyond traditional hydrogels in structural adaptability and multifunctionality.https://doi.org/10.1038/s41467-025-63033-w
spellingShingle Jinrong Wang
Weibin Lin
Valeriia O. Nikolaeva
Rukhma Javaid
Niveen M. Khashab
Designing supramolecular pastes by controlling host–guest dynamics in reconfigurable networks
Nature Communications
title Designing supramolecular pastes by controlling host–guest dynamics in reconfigurable networks
title_full Designing supramolecular pastes by controlling host–guest dynamics in reconfigurable networks
title_fullStr Designing supramolecular pastes by controlling host–guest dynamics in reconfigurable networks
title_full_unstemmed Designing supramolecular pastes by controlling host–guest dynamics in reconfigurable networks
title_short Designing supramolecular pastes by controlling host–guest dynamics in reconfigurable networks
title_sort designing supramolecular pastes by controlling host guest dynamics in reconfigurable networks
url https://doi.org/10.1038/s41467-025-63033-w
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